{"id":"W4402082244","doi":"10.1016/j.placenta.2024.07.126","title":"Excessive hypercholesterolemia in pregnancy induces sex-specific differences in the placental unfolded protein response","year":2024,"lang":"en","type":"article","venue":"Placenta","topic":"Birth, Development, and Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Pregnancy; Unfolded protein response; Medicine; Internal medicine; Endocrinology; Obstetrics; Biology; Cell biology; Genetics; Endoplasmic reticulum","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001645596,0.0001441371,0.0002283987,0.000475541,0.0001826043,0.0003801263,0.0001307937,0.0002077886,0.001407417],"category_scores_gemma":[0.0003016105,0.0002745154,0.0001900424,0.000228907,0.0002759242,0.0001419513,0.0002899618,0.0003832251,0.0001624519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003278608,"about_ca_system_score_gemma":0.0002561967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001020079,"about_ca_topic_score_gemma":0.001403676,"domain_scores_codex":[0.9998403,0.0000427868,0.00001008833,0.0000340171,0.00002493374,0.0000478892],"domain_scores_gemma":[0.9997892,0.00003931483,0.000065001,0.00003725052,0.00001616317,0.00005305182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00171213,0.00004944201,0.005648847,0.0000206337,0.00001746899,0.000224868,0.0001293156,0.00002419321,0.9886579,0.0002770335,0.00007181801,0.003166477],"study_design_scores_gemma":[0.0001153599,0.001023212,0.5008509,0.00002657235,0.0001069247,0.001759387,0.0005949887,0.0004741777,0.4910634,0.0007810022,0.003178472,0.00002553966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974946,0.0009949112,0.0004387176,0.0001111053,0.00001709095,0.000004643394,0.0001305671,0.00002045755,0.000787881],"genre_scores_gemma":[0.9974678,0.0006387074,0.0002425707,0.00004855449,0.000008293412,0.000009993742,0.0001317868,0.00001682421,0.001435517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001407417,"threshold_uncertainty_score":0.00470829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05121861674597815,"score_gpt":0.305213702975083,"score_spread":0.2539950862291049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}