{"id":"W4402082459","doi":"10.1016/j.placenta.2024.07.293","title":"Unfolding the role of endoplasmic reticulum stress and IRE1 signaling in trophoblast differentiation","year":2024,"lang":"en","type":"article","venue":"Placenta","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children’s Health Research Institute; Lawson Health Research Institute; Western University","funders":"","keywords":"Endoplasmic reticulum; Trophoblast; Cell biology; Unfolded protein response; Stress (linguistics); Biology; Pregnancy; Genetics; Placenta; Fetus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000830122,0.00007049611,0.0001313321,0.00004338228,0.00003598144,0.00001491286,0.00003361502,0.00002933811,0.0000228599],"category_scores_gemma":[0.0000315803,0.00004653071,0.00002839414,0.0000980189,0.00004147611,0.00004022565,0.00004079581,0.0001216422,0.000002206112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001857126,"about_ca_system_score_gemma":0.00001407062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003810346,"about_ca_topic_score_gemma":0.00005395161,"domain_scores_codex":[0.9994963,0.00003269654,0.0001380548,0.0001210948,0.0001040041,0.0001078047],"domain_scores_gemma":[0.9996915,0.0001721019,0.00002456927,0.00008346509,0.000009118129,0.00001927688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002848341,0.0001182582,0.7702528,0.001295938,0.0002452104,0.00004256481,0.01024819,0.00007021885,0.2036469,0.003310544,0.0001153265,0.01036924],"study_design_scores_gemma":[0.001743192,0.0001754847,0.144763,0.007730539,0.0003142384,0.0000475759,0.006819542,0.01942047,0.8161739,0.001565758,0.001035756,0.0002105417],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807312,0.01756754,0.00001879799,0.0002849367,0.00009831517,0.0001661659,0.00001156223,0.00002121889,0.001100207],"genre_scores_gemma":[0.9991546,0.0006857549,0.00003091913,0.00001536957,0.00003683191,0.00001106303,0.00000726532,0.000007055196,0.00005109444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6254897,"threshold_uncertainty_score":0.1897467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008094480999102212,"score_gpt":0.2309537479747598,"score_spread":0.2228592669756576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}