{"id":"W4402100088","doi":"10.1093/ecco-jcc/jjae128","title":"Achievement of Endoscopic Remission After Induction Reduces Hospitalization Burden in Crohn’s Disease: Findings From a Pooled Post Hoc Analysis of Risankizumab and Upadacitinib Phase III Trials","year":2024,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Calgary","funders":"AbbVie","keywords":"Medicine; Discontinuation; Crohn's disease; Confidence interval; Internal medicine; Maintenance therapy; Post-hoc analysis; Randomized controlled trial; Clinical endpoint; Clinical trial; Gastroenterology; Surgery; Disease; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04009097,0.002057321,0.007406922,0.001272294,0.0002929458,0.002978465,0.001308548,0.001362126,0.002350275],"category_scores_gemma":[0.05477777,0.0009692869,0.02808952,0.001594194,0.0006656487,0.001655148,0.001200351,0.002361427,0.0002893045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007799002,"about_ca_system_score_gemma":0.001243012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008931958,"about_ca_topic_score_gemma":0.001601618,"domain_scores_codex":[0.9667487,0.02396727,0.003349592,0.003226507,0.001741583,0.0009663163],"domain_scores_gemma":[0.927399,0.04875758,0.01471249,0.005381951,0.002469372,0.001279585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.2121962,0.0002651985,0.07147083,0.005618769,0.6767309,0.0002181869,0.0001714412,0.002251624,0.001289616,0.0001664807,0.001541125,0.02807965],"study_design_scores_gemma":[0.0227638,0.01618054,0.2374776,0.0008798461,0.7134501,0.0003402161,0.0001522766,0.004639383,0.001256033,0.0005610043,0.002177936,0.0001213281],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8129362,0.1681801,0.008731793,0.001147712,0.001007111,0.0007980735,0.004038476,0.0003003916,0.002860111],"genre_scores_gemma":[0.9901599,0.006006974,0.001198212,0.0003725473,0.0003315148,0.0003016275,0.001104305,0.00007150172,0.00045343],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04009097,"threshold_uncertainty_score":0.2120238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009627914990409426,"score_gpt":0.2867320685343867,"score_spread":0.2771041535439772,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}