{"id":"W4402104460","doi":"10.1016/j.jaad.2024.07.1218","title":"51675 Safety and efficacy of risankizumab in adult patients with moderate-to-severe plaque psoriasis with non-pustular palmoplantar involvement: changes in PPASI and PASI from Phase 3b IMMprint trial","year":2024,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Innovaderm (Canada)","funders":"","keywords":"Medicine; Plaque psoriasis; Dermatology; Psoriasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00103182,0.0007683756,0.001554835,0.0002310949,0.0002541743,0.0009477811,0.0004128939,0.001008934,0.004006022],"category_scores_gemma":[0.0008385897,0.0003562311,0.001527879,0.0002068893,0.000417712,0.0005367834,0.000186098,0.002205689,0.00144201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005664212,"about_ca_system_score_gemma":0.0006181128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004518851,"about_ca_topic_score_gemma":0.001342184,"domain_scores_codex":[0.9996618,0.0001273906,0.00002499104,0.00004867448,0.00005230731,0.00008478785],"domain_scores_gemma":[0.9996355,0.00009406676,0.00008121669,0.00002667666,0.00003639066,0.0001262041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7383832,0.006942847,0.01483198,0.001444126,0.003170388,0.0004000697,0.0001690851,0.002375318,0.02363739,0.0006519104,0.01518206,0.1928117],"study_design_scores_gemma":[0.6948348,0.2313045,0.05223862,0.0001947333,0.00218299,0.0009618699,0.00009630269,0.002607964,0.003877859,0.0005977583,0.0110134,0.00008919607],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778217,0.01035931,0.0003840624,0.00114187,0.0003910648,0.0005639158,0.002271264,0.0002193231,0.006847511],"genre_scores_gemma":[0.9881754,0.002616293,0.0004656884,0.001852845,0.0002723637,0.0002918349,0.002951062,0.0000253046,0.003349188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004006022,"threshold_uncertainty_score":0.01340151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008949594487291372,"score_gpt":0.2488106264001959,"score_spread":0.2398610319129045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}