{"id":"W4402106923","doi":"10.1016/j.jaad.2024.07.927","title":"51876 Impact of Long-Term Abrocitinib Treatment on Patient-Reported Outcomes and Quality of Life for Approximately 2 Years in Patients With Moderate-to-Severe Atopic Dermatitis: An Interim Analysis of JADE EXTEND, a Long-Term Extension Study","year":2024,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Probity Medical Research; SKiN Health; Queen's University","funders":"","keywords":"Medicine; Atopic dermatitis; JADE (particle detector); Quality of life (healthcare); Interim analysis; Interim; Term (time); Dermatology; Surgery; Randomized controlled trial; Nursing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003518537,0.0006906396,0.002052069,0.0003437806,0.0004298585,0.001375708,0.0005109948,0.0007078103,0.001876041],"category_scores_gemma":[0.002286515,0.0002495804,0.004681118,0.0005057202,0.0003768441,0.0009321118,0.0005399411,0.001957994,0.0003895493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005077079,"about_ca_system_score_gemma":0.0006265694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007883906,"about_ca_topic_score_gemma":0.001624633,"domain_scores_codex":[0.9987724,0.0005196178,0.0001123424,0.0001698583,0.0001741988,0.0002514366],"domain_scores_gemma":[0.9979922,0.0005540131,0.0006684784,0.0002798566,0.000173125,0.0003323472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5701798,0.007026381,0.3080938,0.001042211,0.02001633,0.0003899978,0.0002034513,0.002926909,0.004110056,0.0002342054,0.002567549,0.08320928],"study_design_scores_gemma":[0.05062754,0.09660839,0.826169,0.0002162883,0.01884138,0.000430406,0.0002607254,0.002152011,0.001359582,0.000266873,0.002957514,0.0001104486],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929073,0.004399459,0.0001771614,0.0001229568,0.00006937223,0.00008285581,0.001361178,0.00001468293,0.0008649897],"genre_scores_gemma":[0.9951501,0.0008174799,0.0002017368,0.000245801,0.00009709864,0.0001381767,0.002648663,0.000005572251,0.0006954661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003518537,"threshold_uncertainty_score":0.01860803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0404592709399291,"score_gpt":0.3844992124744943,"score_spread":0.3440399415345652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}