{"id":"W4402135725","doi":"10.1080/22221751.2024.2399949","title":"Novel recombinant vaccinia virus-vectored vaccine affords complete protection against homologous <i>Borrelia burgdorferi</i> infection in mice","year":2024,"lang":"en","type":"article","venue":"Emerging Microbes & Infections","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University; National Research Council Canada; Public Health Agency of Canada; University of Ottawa; Health Canada","funders":"Health Canada; Government of Canada","keywords":"Virology; Borrelia burgdorferi; Vaccinia; Biology; Recombinant DNA; Virus; Orthopoxvirus; Vector (molecular biology); Modified vaccinia Ankara; Poxviridae; Recombinant virus; Microbiology; Antibody; Gene; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001944357,0.0007039533,0.0005186704,0.000309592,0.0001211122,0.0003190916,0.000281747,0.0006721824,0.0004849558],"category_scores_gemma":[0.0001404644,0.0002145925,0.0003776615,0.0001158142,0.0002743388,0.0003675396,0.0001392291,0.001084661,0.0002276193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002939224,"about_ca_system_score_gemma":0.0002556591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003493825,"about_ca_topic_score_gemma":0.0003620721,"domain_scores_codex":[0.9998075,0.00001973237,0.00002187234,0.00005002058,0.00003098281,0.000069857],"domain_scores_gemma":[0.9998566,0.00002046408,0.00005004612,0.0000156187,0.00001633008,0.00004093756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003895204,0.0002494941,0.0001255521,0.00006686132,0.00001247273,0.00003493292,0.00001689653,0.0001355199,0.9970664,0.0001030344,0.00006823248,0.001731042],"study_design_scores_gemma":[0.0002529672,0.006516885,0.004233131,0.00002448185,0.00008670732,0.0004164655,0.00002465295,0.002308709,0.9825979,0.00009685132,0.003428472,0.0000127606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928764,0.001587853,0.003701456,0.0001327934,0.00009687114,0.00007300637,0.0003259812,0.0001969359,0.001008731],"genre_scores_gemma":[0.991674,0.001106893,0.003994686,0.0001271478,0.0000531912,0.00007499787,0.001141293,0.00004365398,0.001784198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007039533,"threshold_uncertainty_score":0.002132595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01366506806924948,"score_gpt":0.2469578310617107,"score_spread":0.2332927629924612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}