{"id":"W4402135725","doi":"10.1080/22221751.2024.2399949","title":"Novel recombinant vaccinia virus-vectored vaccine affords complete protection against homologous <i>Borrelia burgdorferi</i> infection in mice","year":2024,"lang":"en","type":"article","venue":"Emerging Microbes & Infections","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University; National Research Council Canada; Public Health Agency of Canada; University of Ottawa; Health Canada","funders":"Health Canada; Government of Canada","keywords":"Virology; Borrelia burgdorferi; Vaccinia; Biology; Recombinant DNA; Virus; Orthopoxvirus; Vector (molecular biology); Modified vaccinia Ankara; Poxviridae; Recombinant virus; Microbiology; Antibody; Gene; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004891931,0.0006835076,0.0006595026,0.00142417,0.0007823202,0.000170403,0.0002468367,0.0005461577,0.0007426395],"category_scores_gemma":[0.0002322997,0.0007146682,0.0004374779,0.002051704,0.0001243144,0.0005622823,0.0001989631,0.001336188,0.001465541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007192455,"about_ca_system_score_gemma":0.0002382201,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01276116,"about_ca_topic_score_gemma":0.01241221,"domain_scores_codex":[0.9964998,0.0003442884,0.0009832736,0.001098839,0.00008497702,0.0009887696],"domain_scores_gemma":[0.9987304,0.0002181326,0.000227597,0.0005389627,0.0002004454,0.00008444654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001227848,0.0012237,0.007564704,0.0001651479,0.0004678243,0.00002871372,0.0004492127,0.001156025,0.9772921,0.0002432837,0.006662861,0.004623604],"study_design_scores_gemma":[0.007924709,0.002692142,0.2365451,0.001845804,0.0009333972,0.0039603,0.0002212509,0.001665433,0.2396469,0.0005425644,0.5005104,0.003512051],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9754345,0.003822885,0.005610385,0.0005037584,0.01070889,0.001247491,0.0001983735,0.00177232,0.0007013928],"genre_scores_gemma":[0.9963516,0.001132972,0.00008416607,0.0002004203,0.0002151073,0.0005538629,0.0004632341,0.0001434847,0.0008551598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7376453,"threshold_uncertainty_score":0.9995304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01366506806924948,"score_gpt":0.2469578310617107,"score_spread":0.2332927629924612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}