{"id":"W4402142135","doi":"10.1093/dote/doae057.044","title":"265. INITIAL RESULTS FROM RESOLVE, A PHASE 1B DOSE-ESCALATION STUDY OF EP-104GI (EXTENDED-RELEASE FLUTICASONE PROPIONATE INTRA-ESOPHAGEAL INJECTION) FOR EOSINOPHILIC ESOPHAGITIS","year":2024,"lang":"en","type":"article","venue":"Diseases of the Esophagus","topic":"Eosinophilic Esophagitis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Aurinia (Canada)","funders":"","keywords":"Eosinophilic esophagitis; Medicine; Fluticasone propionate; Fluticasone; Gastroenterology; Internal medicine; Corticosteroid; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001669772,0.000848101,0.001150669,0.0003100877,0.0003523348,0.0008656143,0.000568399,0.001186512,0.009339817],"category_scores_gemma":[0.0009503283,0.000426662,0.001072489,0.0002600347,0.000425748,0.0004854005,0.0002457931,0.002172199,0.002991057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005593563,"about_ca_system_score_gemma":0.001188043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007455833,"about_ca_topic_score_gemma":0.002310237,"domain_scores_codex":[0.9995002,0.0001946072,0.00003990345,0.00007547543,0.000113832,0.00007598771],"domain_scores_gemma":[0.9994327,0.0001093985,0.0001056485,0.00004012827,0.0001045331,0.000207504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4204911,0.04901954,0.008306755,0.004604062,0.00197805,0.000805812,0.0003102132,0.002582625,0.1398753,0.001021848,0.05656659,0.314438],"study_design_scores_gemma":[0.4080664,0.4768746,0.03655168,0.0003479392,0.001548635,0.0009107383,0.000100934,0.001356756,0.01607589,0.0005069121,0.0575969,0.00006259831],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8908178,0.02017377,0.003612194,0.003193603,0.0008680227,0.01869436,0.02662618,0.0009865536,0.03502758],"genre_scores_gemma":[0.9216213,0.008175645,0.006985684,0.005900921,0.0006025759,0.008979849,0.0249601,0.0001852408,0.02258863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009339817,"threshold_uncertainty_score":0.03124475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02160293372587004,"score_gpt":0.3247991865336321,"score_spread":0.3031962528077621,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}