{"id":"W4402160549","doi":"10.1007/978-3-031-63366-9_8","title":"Acute Promyelocytic Leukemia","year":2024,"lang":"en","type":"book-chapter","venue":"Pediatric oncology","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Acute promyelocytic leukemia; Medicine; Cancer research; Biology; Genetics; Retinoic acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001815095,0.0005244676,0.0005292455,0.0001792895,0.00007623316,0.00003864277,0.0004923588,0.001668021,0.0003406112],"category_scores_gemma":[0.00003867412,0.000496224,0.0003174896,0.00006030033,0.0001603795,0.000002832089,0.0004051015,0.0007136397,0.001302281],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004229257,"about_ca_system_score_gemma":0.002438809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002718279,"about_ca_topic_score_gemma":0.000006484624,"domain_scores_codex":[0.9978665,0.00002129642,0.0004900363,0.0009473209,0.0002409661,0.0004338713],"domain_scores_gemma":[0.9988325,0.00003356859,0.0002527607,0.0005801978,0.0001356997,0.0001652894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008270011,0.0001829363,0.0003056943,0.00419705,0.003673903,0.004950198,0.0002933893,0.00008571423,0.03010803,0.1049326,0.8016077,0.04883581],"study_design_scores_gemma":[0.0003969893,0.0008063695,0.000002787248,0.00001881689,0.001086436,0.0003271812,0.000005193455,0.00001098887,0.001827935,0.009594005,0.9853335,0.0005897933],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.00395252,0.02061387,0.0001253332,0.0001745573,0.001883787,0.0004266279,0.0000890731,0.00009554889,0.9726387],"genre_scores_gemma":[0.008634463,0.02057661,0.0004259856,0.0002903085,0.007118789,0.00007342383,0.0005976434,0.0001930679,0.9620897],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.1837258,"threshold_uncertainty_score":0.9997489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00903278565665089,"score_gpt":0.2611486713228967,"score_spread":0.2521158856662458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}