{"id":"W4402168894","doi":"10.3390/ijms25179493","title":"An Inducible Luminescent System to Explore Parkinson’s Disease-Associated Genes","year":2024,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Health Canada; Montreal Neurological Institute and Hospital","funders":"","keywords":"Biology; Induced pluripotent stem cell; Gene; HEK 293 cells; Cell biology; Genetics; Molecular biology; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004199078,0.0006943594,0.0004500984,0.0005060741,0.0001949495,0.0005010348,0.0005428373,0.000586469,0.002219754],"category_scores_gemma":[0.0001828029,0.0002928009,0.0003970056,0.0003077443,0.0003460799,0.0003555356,0.0005853148,0.001296594,0.001172198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004647111,"about_ca_system_score_gemma":0.0002226016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002133702,"about_ca_topic_score_gemma":0.0003281184,"domain_scores_codex":[0.999626,0.00006903331,0.00002497154,0.0001356842,0.000093427,0.0000507219],"domain_scores_gemma":[0.9998617,0.00003525958,0.0000341802,0.00002403231,0.00001738639,0.00002736239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000035995,0.00002470435,0.00006590389,0.00004839285,0.000004115416,0.00002547083,0.00001827009,0.00007245875,0.9972588,0.0003954166,0.0001437812,0.00190672],"study_design_scores_gemma":[0.00001903511,0.0001769277,0.0004609473,0.00001202794,0.00001680507,0.0001544495,0.00001369836,0.001371915,0.9868107,0.0001134872,0.01083971,0.00001035486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5357004,0.005733442,0.4360108,0.0008130981,0.0004277781,0.0006384135,0.004000639,0.004497102,0.01217817],"genre_scores_gemma":[0.7590798,0.004371871,0.2010738,0.0007207519,0.0000862042,0.001842712,0.00792935,0.0006976194,0.02419789],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002219754,"threshold_uncertainty_score":0.007425845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01981898079279835,"score_gpt":0.3362793317654971,"score_spread":0.3164603509726987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}