{"id":"W4402171729","doi":"10.1021/acsnano.4c02940","title":"Mitochondrial Extracellular Vesicles: A Promising Avenue for Diagnosing and Treating Lung Diseases","year":2024,"lang":"en","type":"review","venue":"ACS Nano","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Chongqing Municipal Education Commission; Natural Science Foundation of Chongqing; China Postdoctoral Science Foundation; Chongqing Municipal Health Commission; Chongqing Science and Technology Commission; Chongqing Postdoctoral Science Foundation","keywords":"Mitochondrion; Biology; Biogenesis; Cell biology; Mitophagy; Mitochondrial biogenesis; Pulmonary fibrosis; Extracellular; Organelle biogenesis; mitochondrial fusion; Bioinformatics; Fibrosis; Medicine; Pathology; Mitochondrial DNA; Apoptosis; Biochemistry; Autophagy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004471952,0.0008146861,0.001078826,0.001915988,0.0003146527,0.00105967,0.0007102888,0.001200861,0.004299772],"category_scores_gemma":[0.0004718733,0.0002382857,0.0004777573,0.001097463,0.0004541741,0.001617714,0.001038936,0.00215836,0.002156625],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000578651,"about_ca_system_score_gemma":0.0008090964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005260244,"about_ca_topic_score_gemma":0.0009113984,"domain_scores_codex":[0.9998221,0.00003091077,0.00001563179,0.00003041872,0.00007982861,0.00002115526],"domain_scores_gemma":[0.9998419,0.00006606294,0.00001713257,0.000007070894,0.00004554795,0.00002222696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006943149,0.00007985337,0.0001374715,0.01161774,0.00008477832,0.0002357747,0.00007459817,0.0004509661,0.008607923,0.01397994,0.03588864,0.9287728],"study_design_scores_gemma":[0.00001083281,0.000083701,0.0002274082,0.001158477,0.00004480221,0.000559787,0.00003560999,0.0001210411,0.001326593,0.002469515,0.9939467,0.0000154433],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002093551,0.9964233,0.0005955001,0.0004725094,0.0004365256,0.000009886844,0.00003620533,0.00002234979,0.001794362],"genre_scores_gemma":[0.001366563,0.9965379,0.0004679544,0.0002675205,0.0002111854,0.00001535111,0.00005891657,0.000003705833,0.001070941],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004299772,"threshold_uncertainty_score":0.01438415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01864079867511542,"score_gpt":0.3163845821220197,"score_spread":0.2977437834469043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}