{"id":"W4402171729","doi":"10.1021/acsnano.4c02940","title":"Mitochondrial Extracellular Vesicles: A Promising Avenue for Diagnosing and Treating Lung Diseases","year":2024,"lang":"en","type":"review","venue":"ACS Nano","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Chongqing Municipal Education Commission; Natural Science Foundation of Chongqing; China Postdoctoral Science Foundation; Chongqing Municipal Health Commission; Chongqing Science and Technology Commission; Chongqing Postdoctoral Science Foundation","keywords":"Mitochondrion; Biology; Biogenesis; Cell biology; Mitophagy; Mitochondrial biogenesis; Pulmonary fibrosis; Extracellular; Organelle biogenesis; mitochondrial fusion; Bioinformatics; Fibrosis; Medicine; Pathology; Mitochondrial DNA; Apoptosis; Biochemistry; Autophagy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001380377,0.0005566153,0.0008052206,0.0001070764,0.0001874059,0.0002248751,0.0002999551,0.0004306495,0.000003305877],"category_scores_gemma":[0.0003597477,0.000503918,0.0005599943,0.0001403597,0.0001240199,0.000009238262,0.0002599909,0.0001840073,0.00001090863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005999067,"about_ca_system_score_gemma":0.000321822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002467129,"about_ca_topic_score_gemma":0.000001573669,"domain_scores_codex":[0.9977639,0.0001110405,0.0005537709,0.0009756674,0.0001560809,0.0004395492],"domain_scores_gemma":[0.9987808,0.0001231424,0.0002639589,0.0005846514,0.00004775841,0.0001997287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006264934,0.0001830105,0.00003367541,0.04401158,0.0006995972,0.0001634981,0.0000992999,0.000001190982,0.034809,0.00009676105,0.009022236,0.9108175],"study_design_scores_gemma":[0.0004362737,0.0001094408,9.006096e-7,0.009161899,0.003774831,0.00006000633,0.00001753377,0.00002771652,0.002515252,0.000127409,0.9831122,0.0006565573],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002609038,0.9941954,0.0003131347,0.0000135948,0.0006823781,0.001636989,0.000475867,0.00004564969,0.00002794072],"genre_scores_gemma":[0.0006627021,0.9926195,0.001181805,0.00001882868,0.002628056,0.0006308735,0.001076899,0.0002198502,0.0009614667],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9740899,"threshold_uncertainty_score":0.9997413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01864079867511542,"score_gpt":0.3163845821220197,"score_spread":0.2977437834469043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}