{"id":"W4402184323","doi":"10.1182/blood.2024025679","title":"Clinical features, pathophysiology, and management of acute myelopathy following CAR T-cell therapy","year":2024,"lang":"en","type":"review","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Royal College of Physicians and Surgeons of Canada","keywords":"Cytokine release syndrome; Medicine; Chimeric antigen receptor; Myelopathy; Cell therapy; Pathophysiology; Immunology; Immunotherapy; Intensive care medicine; Myelitis; Immune system; Internal medicine; Cell; Spinal cord; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002956148,0.0005165051,0.0006906656,0.001643937,0.0002379536,0.000661426,0.0005787205,0.0008757001,0.001127551],"category_scores_gemma":[0.0007452349,0.0001117844,0.0003027476,0.001021876,0.0003900959,0.0006104221,0.0003538737,0.0008715247,0.0007194016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000343689,"about_ca_system_score_gemma":0.0006728689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006569191,"about_ca_topic_score_gemma":0.0009196571,"domain_scores_codex":[0.9998528,0.00003579256,0.00002939682,0.00002321951,0.00004252714,0.00001617129],"domain_scores_gemma":[0.9998142,0.00008937898,0.0000406037,0.000005532553,0.00003840653,0.00001191489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008906743,0.0000614105,0.001666207,0.01772642,0.0001482005,0.01069595,0.0001869839,0.0004605456,0.002652494,0.002726943,0.02406178,0.9395239],"study_design_scores_gemma":[0.00003922959,0.000222252,0.009071982,0.02117644,0.0005555773,0.2031973,0.000586159,0.0004425501,0.002821014,0.005053862,0.7567618,0.0000718687],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008218049,0.9965991,0.0002593317,0.0004329163,0.0001779322,0.000007168583,0.00001712192,0.00001024553,0.001674451],"genre_scores_gemma":[0.007502568,0.9910383,0.0003121869,0.0003422394,0.0003319288,0.000008135728,0.00003606314,0.000001821623,0.0004268251],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001643937,"threshold_uncertainty_score":0.00377202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05500001030193057,"score_gpt":0.4044169536801847,"score_spread":0.3494169433782541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}