{"id":"W4402201486","doi":"10.1016/j.healun.2024.08.018","title":"Safety and efficacy of riociguat in patients with pulmonary arterial hypertension and cardiometabolic comorbidities: Data from interventional clinical trials","year":2024,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Riociguat; Medicine; Clinical trial; Internal medicine; Cardiology; Pulmonary hypertension; Chronic thromboembolic pulmonary hypertension; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002599015,0.0008530436,0.003118309,0.0003628605,0.0002060204,0.001205471,0.0006452445,0.001080546,0.001452626],"category_scores_gemma":[0.004012276,0.0003096794,0.002396093,0.0005162974,0.0008100665,0.0009233684,0.0002775016,0.002153238,0.0003116309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005935299,"about_ca_system_score_gemma":0.0005368451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004490087,"about_ca_topic_score_gemma":0.001092062,"domain_scores_codex":[0.9988777,0.0005004744,0.0001522816,0.0001997022,0.0001503571,0.0001193767],"domain_scores_gemma":[0.9973704,0.001221031,0.0008864532,0.000172196,0.0001441089,0.0002057727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6937699,0.002930603,0.04674337,0.01029787,0.03234324,0.0003652514,0.0001989647,0.001731575,0.01083095,0.0007619642,0.005264518,0.1947618],"study_design_scores_gemma":[0.5136859,0.08286029,0.3240853,0.002079054,0.04631869,0.001328373,0.0003359358,0.002847732,0.00571293,0.002197613,0.01832018,0.000228047],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7770443,0.2092477,0.0009809184,0.002381395,0.0004924863,0.0004372664,0.002376702,0.0001364845,0.006902792],"genre_scores_gemma":[0.9695608,0.02472044,0.0006372056,0.001859117,0.0004565531,0.0002746781,0.00192462,0.00002544919,0.0005411959],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003118309,"threshold_uncertainty_score":0.01374507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09183600528606495,"score_gpt":0.3885462153879691,"score_spread":0.2967102101019042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}