{"id":"W4402214749","doi":"10.1097/shk.0000000000002457","title":"IMPACT OF ABCC8 AND TRPM4 GENETIC VARIATION IN CENTRAL NERVOUS SYSTEM DYSFUNCTION ASSOCIATED WITH PEDIATRIC SEPSIS","year":2024,"lang":"en","type":"article","venue":"Shock","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Allergy and Infectious Diseases; Philips Research Americas; National Institutes of Health; U.S. Department of Defense; Mallinckrodt Pharmaceuticals; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences","keywords":"Sepsis; Medicine; Central nervous system; Organ dysfunction; Glasgow Coma Scale; Internal medicine; Bioinformatics; Anesthesia; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006715907,0.0004048148,0.0003551656,0.0005776579,0.0002419206,0.0004655511,0.0003250547,0.0003588946,0.002402319],"category_scores_gemma":[0.002257847,0.0001547117,0.0005734939,0.000958604,0.0003424594,0.0002492501,0.0004135621,0.0004082659,0.0001303278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002064111,"about_ca_system_score_gemma":0.0002597257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002863467,"about_ca_topic_score_gemma":0.001763573,"domain_scores_codex":[0.9992031,0.0002197434,0.00007578416,0.0002948557,0.0001421913,0.00006432086],"domain_scores_gemma":[0.9985107,0.0004414789,0.0006982999,0.0001011524,0.0001226176,0.0001257197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002153741,0.000009644141,0.9956818,0.00002107459,0.0002674399,0.0002742807,0.00004151568,0.000136446,0.001451457,0.00004062481,0.00007381016,0.001786547],"study_design_scores_gemma":[0.000008211462,0.00006058371,0.9975659,0.00001613631,0.0001594233,0.0009807945,0.00007046961,0.0004819401,0.000403898,0.00005097749,0.0001985865,0.000003131452],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985575,0.0005862672,0.0003103594,0.00004063962,0.00000515554,0.000003095184,0.0003297199,0.000004897483,0.0001623902],"genre_scores_gemma":[0.9994448,0.0001255979,0.0001759629,0.0000108285,0.000005808202,0.000002870318,0.0001866315,0.000003693478,0.00004379779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002863467,"threshold_uncertainty_score":0.008036494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01236822738097046,"score_gpt":0.2364784645859401,"score_spread":0.2241102372049697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}