{"id":"W4402214749","doi":"10.1097/shk.0000000000002457","title":"IMPACT OF ABCC8 AND TRPM4 GENETIC VARIATION IN CENTRAL NERVOUS SYSTEM DYSFUNCTION ASSOCIATED WITH PEDIATRIC SEPSIS","year":2024,"lang":"en","type":"article","venue":"Shock","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Allergy and Infectious Diseases; Philips Research Americas; National Institutes of Health; U.S. Department of Defense; Mallinckrodt Pharmaceuticals; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences","keywords":"Sepsis; Medicine; Central nervous system; Organ dysfunction; Glasgow Coma Scale; Internal medicine; Bioinformatics; Anesthesia; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007733067,0.00008769364,0.000115884,0.0001468694,0.00003468029,0.0000367404,0.00004036084,0.00006454926,0.00002327122],"category_scores_gemma":[0.00005224055,0.00006080099,0.00004015729,0.0005561955,0.0000151078,0.00008147921,0.00001230762,0.0000852464,0.000006107424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001606232,"about_ca_system_score_gemma":0.00006652303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001652699,"about_ca_topic_score_gemma":0.00001646167,"domain_scores_codex":[0.9992177,0.00007781494,0.0001535487,0.0002147552,0.000155609,0.0001805705],"domain_scores_gemma":[0.999756,0.00007766381,0.00005470542,0.00004893461,0.0000176231,0.00004509644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007033871,0.000862145,0.457835,0.002697922,0.0002589276,0.0004443362,0.01894695,0.1026004,0.3857641,0.001252687,0.003317402,0.0253168],"study_design_scores_gemma":[0.0004879305,0.000455355,0.9136186,0.0001133551,0.00006145333,0.00002269738,0.00007602988,0.08187239,0.003083826,0.00004111058,0.00000747064,0.0001598186],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985502,0.0001244529,0.0003841088,0.00002039234,0.0005545113,0.0001477917,0.00001757062,0.00005975788,0.0001412589],"genre_scores_gemma":[0.9996634,0.00005493592,0.00001428622,0.000005203649,0.0001152223,0.000003478217,0.000002284595,0.00001296522,0.0001282115],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4557836,"threshold_uncertainty_score":0.2479393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01236822738097046,"score_gpt":0.2364784645859401,"score_spread":0.2241102372049697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}