{"id":"W4402236088","doi":"10.1128/mbio.01002-24","title":"The HmrABCX pathway regulates the transition between motile and sessile lifestyles in <i>Caulobacter crescentus</i> by a mechanism independent of <i>hfiA</i> transcription","year":2024,"lang":"en","type":"article","venue":"mBio","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Common Fund; National Institutes of Health; Université de Montréal; National Institute of General Medical Sciences; Canada Research Chairs","keywords":"Caulobacter crescentus; Biology; Biofilm; Flagellum; Cell biology; Holdfast; Histidine kinase; Response regulator; Genetic screen; Chemotaxis; Regulator; Motility; Genetics; Gene; Mutant; Microbiology; Bacteria; Cell cycle; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001417694,0.000464211,0.0002283163,0.0003005424,0.0002486143,0.0004441269,0.0002451822,0.0002154125,0.0007193239],"category_scores_gemma":[0.0001365496,0.000168757,0.0002200881,0.0001109573,0.0002718947,0.0001831295,0.0003401745,0.0003793488,0.0002882352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007936961,"about_ca_system_score_gemma":0.0004308636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004691525,"about_ca_topic_score_gemma":0.003847113,"domain_scores_codex":[0.99984,0.00002003134,0.000008946728,0.00003801955,0.00003869326,0.00005423028],"domain_scores_gemma":[0.9998239,0.00002144237,0.00005238434,0.00001886494,0.00002476484,0.00005857018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003592428,0.00001091522,0.0001979179,0.00001132596,0.00000162866,0.00002129416,0.00000849872,0.0000296378,0.9992177,0.00004239762,0.00002114878,0.000401557],"study_design_scores_gemma":[0.00002823115,0.0001734808,0.02497957,0.00001237156,0.00001586349,0.000194548,0.0001023235,0.002639243,0.9703696,0.00009141284,0.001375916,0.00001750207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966751,0.0005878535,0.001157856,0.0001193414,0.00001254268,0.00001927155,0.0004229301,0.0001750992,0.0008298559],"genre_scores_gemma":[0.9969222,0.0001600062,0.001031193,0.00005719509,0.000004128683,0.0000146052,0.000492233,0.00003990619,0.001278507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004691525,"threshold_uncertainty_score":0.009328425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005101721119908953,"score_gpt":0.1999183189522556,"score_spread":0.1948165978323466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}