{"id":"W4402237267","doi":"10.1038/s42003-024-06756-8","title":"Strain heterogeneity in a non-pathogenic Aspergillus fungus highlights factors associated with virulence","year":2024,"lang":"en","type":"article","venue":"Communications Biology","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Azrieli Foundation; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Canadian Institutes of Health Research; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo; National Institutes of Health; National Science Foundation; U.S. Department of Health and Human Services; Vanderbilt University","keywords":"Virulence; Microbiology; Fungus; Aspergillus; Strain (injury); Biology; Pathogenic fungus; Genetics; Gene; Botany","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002525317,0.0001657664,0.0001577438,0.0001230399,0.0001170445,0.0000328727,0.0008173927,0.000224368,0.00002018517],"category_scores_gemma":[0.00008977237,0.000129322,0.00007064467,0.0003349522,0.0003102821,0.000004334051,0.0004495867,0.0002481865,0.00002312432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004622301,"about_ca_system_score_gemma":0.0001426755,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004164535,"about_ca_topic_score_gemma":0.001887021,"domain_scores_codex":[0.9987369,0.0002755014,0.0002100473,0.0003775547,0.00007768733,0.000322279],"domain_scores_gemma":[0.9986624,0.00009116214,0.00003574792,0.001050836,0.00007912696,0.00008069872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002141417,0.000122294,0.01669926,0.00001117806,0.0001037505,0.000004332761,0.0001001299,0.00002874009,0.9801764,0.0008316513,0.00006528701,0.001835544],"study_design_scores_gemma":[0.002618541,0.004146297,0.3760137,0.0004607081,0.0001320029,0.00006426846,0.0004763448,0.01037719,0.5160702,0.001711379,0.08583345,0.002095936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991202,0.00652031,0.0002784226,0.0004236746,0.00008158341,0.0002133825,0.0002662263,0.00002771128,0.0009866917],"genre_scores_gemma":[0.9969062,0.001312978,0.0002648494,0.00005035164,0.00003201331,0.00006680653,0.001129383,0.00002216146,0.0002153017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4641063,"threshold_uncertainty_score":0.52736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04271151677679786,"score_gpt":0.3263921685833854,"score_spread":0.2836806518065875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}