{"id":"W4402250203","doi":"10.1136/bcr-2024-259860","title":"Refractory amiodarone-induced thyrotoxicosis requiring adjunctive cholestyramine treatment","year":2024,"lang":"en","type":"article","venue":"BMJ Case Reports","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Levothyroxine; Amiodarone; Cholestyramine; Refractory (planetary science); Prednisone; Adjunctive treatment; Thyroidectomy; Antithyroid agent; Euthyroid; Internal medicine; Gastroenterology; Thyroid; Atrial fibrillation; Graves' disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002180072,0.0001848964,0.0001389524,0.00008380808,0.00009587724,0.00005150388,0.00001843741,0.0001661716,0.00005366524],"category_scores_gemma":[0.00007337316,0.0001565858,0.0001455902,0.0001112301,0.0000285946,0.00001098045,0.00003653003,0.00006876018,0.00002326154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001181793,"about_ca_system_score_gemma":0.000125396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004918653,"about_ca_topic_score_gemma":0.0000327171,"domain_scores_codex":[0.9988013,0.00004335677,0.0003212001,0.0005018035,0.0001428133,0.0001895177],"domain_scores_gemma":[0.99931,0.000009564783,0.0001003195,0.0004079198,0.00007231352,0.00009988288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001450631,0.0002505459,0.0002752712,0.0000690622,0.0002771109,0.1359943,0.0002790358,0.0002499704,0.7875828,0.00007291674,0.00427929,0.0705246],"study_design_scores_gemma":[0.0006837099,0.001472118,0.0008584104,0.0001131354,0.0001310506,0.2687155,0.0003506042,0.001352723,0.4280372,0.0001043731,0.2975356,0.0006455351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932183,0.0006162117,0.001046995,0.0001908611,0.001686531,0.0005177431,0.000006876348,0.00008776734,0.002628695],"genre_scores_gemma":[0.9944401,0.00005821278,0.0000845949,0.00006168537,0.001232665,0.0001596893,0.0001993039,0.00003461311,0.003729116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3595456,"threshold_uncertainty_score":0.6385382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03274569432078095,"score_gpt":0.3202195808842637,"score_spread":0.2874738865634828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}