{"id":"W4402266527","doi":"10.1158/1538-7445.pediatric24-pr003","title":"Abstract PR003: Canada’s path towards proteome guided therapies and advanced molecular pathology in pediatric precision oncology","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Calgary; Children's Hospital of Eastern Ontario; McGill University; University of British Columbia","funders":"","keywords":"Pediatric oncology; Medicine; Precision oncology; Molecular pathology; Precision medicine; Oncology; Medical physics; Pathology; Internal medicine; Cancer; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01042554,0.0006401321,0.0004687537,0.001372769,0.004568561,0.006727423,0.002424107,0.003437995,0.01518031],"category_scores_gemma":[0.01195525,0.0005211626,0.000713165,0.001904109,0.004949575,0.002890961,0.004804,0.006966417,0.002237192],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.06941279,"about_ca_system_score_gemma":0.2282414,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.8314499,"about_ca_topic_score_gemma":0.9005211,"domain_scores_codex":[0.9937006,0.001183368,0.0002130482,0.0005250182,0.00322087,0.001156977],"domain_scores_gemma":[0.957195,0.003732875,0.001403218,0.001727759,0.02171953,0.01422177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003888708,0.0001324816,0.02969096,0.001137347,0.0001040712,0.001407996,0.001223341,0.001755695,0.006569208,0.102745,0.6223482,0.2324969],"study_design_scores_gemma":[0.00007583547,0.0001688677,0.0240591,0.001233212,0.00003602488,0.0006907614,0.001111675,0.001441626,0.002909341,0.01242549,0.9557492,0.0000988025],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.02494436,0.03841863,0.01753277,0.8243833,0.006510785,0.0003556666,0.003791278,0.001266739,0.08279658],"genre_scores_gemma":[0.4245569,0.07978998,0.1190151,0.2526554,0.004528818,0.0004797982,0.006298675,0.001406492,0.1112687],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.9305872,"threshold_uncertainty_score":0.5036274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03087254620961161,"score_gpt":0.3788371208763839,"score_spread":0.3479645746667723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}