{"id":"W4402266824","doi":"10.1158/1538-7445.pediatric24-b029","title":"Abstract B029: Studies in human bone cell co-cultures reveal a potential mechanism underlying bone fractures in children treated with entrectinib and suggest a positive association with vitamin D","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Bone health and treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Mechanism (biology); Medicine; Internal medicine; Bioinformatics; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003591664,0.0003095843,0.0004423494,0.000396982,0.0002588145,0.0004073412,0.0002751193,0.0005485796,0.00452809],"category_scores_gemma":[0.0002534778,0.0001564174,0.0004043893,0.0004983273,0.0002061182,0.0001447556,0.0002370467,0.0006050037,0.0009783086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002367343,"about_ca_system_score_gemma":0.000326098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002810773,"about_ca_topic_score_gemma":0.003961715,"domain_scores_codex":[0.9995259,0.00008072297,0.00005344532,0.00009108157,0.0001784107,0.00007038326],"domain_scores_gemma":[0.9997928,0.00006163327,0.00004565569,0.00002662616,0.00004551336,0.00002786419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001372558,0.0002886007,0.006459514,0.0003139912,0.00004561373,0.0007566337,0.0001234097,0.000153466,0.9811358,0.0001216011,0.0004662724,0.008762606],"study_design_scores_gemma":[0.0001701372,0.005700414,0.1004347,0.0000905214,0.0001254564,0.005945209,0.0006155504,0.0009050469,0.8692832,0.0001209756,0.01658301,0.00002564455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815599,0.007923464,0.003130223,0.000269037,0.00006931736,0.0000967086,0.003345039,0.00005780128,0.003548651],"genre_scores_gemma":[0.9851431,0.002983338,0.002457349,0.0001670017,0.00002353769,0.000109612,0.004948449,0.00001333023,0.004154323],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00452809,"threshold_uncertainty_score":0.01514792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.047542767719168,"score_gpt":0.4352427419818631,"score_spread":0.3876999742626951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}