{"id":"W4402267146","doi":"10.1158/1538-7445.pediatric24-ia026","title":"Abstract IA026: Are we ready to accelerate the development of new safe and effective anticancer medicines for children and adolescents?","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Intensive care medicine; Pharmacology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01018332,0.0007134376,0.0007475783,0.0006834629,0.000974689,0.005808835,0.001395209,0.004574487,0.04723453],"category_scores_gemma":[0.02496645,0.000228161,0.001288063,0.0007233687,0.00130726,0.005328764,0.002784825,0.008733335,0.01594263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003242651,"about_ca_system_score_gemma":0.01264225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003224059,"about_ca_topic_score_gemma":0.003731497,"domain_scores_codex":[0.9966033,0.001400195,0.0002919814,0.0002918514,0.001049291,0.0003634103],"domain_scores_gemma":[0.9759949,0.004793413,0.002675657,0.0008883775,0.009162246,0.006485386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007766543,0.0001433741,0.001816711,0.002152884,0.00009378808,0.000177585,0.0001301713,0.0002425939,0.0008355977,0.01905136,0.6349538,0.3396256],"study_design_scores_gemma":[0.0002409543,0.0003798484,0.002080149,0.004932774,0.00009832809,0.0003182842,0.0002787766,0.0002085301,0.0007389532,0.01060376,0.9800868,0.00003283452],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.005039465,0.1652396,0.003337953,0.7477992,0.03795638,0.0002090066,0.002398359,0.000600997,0.03741909],"genre_scores_gemma":[0.06577297,0.213246,0.01517829,0.5653365,0.04349764,0.0007292741,0.003597111,0.0006358537,0.09200642],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04723453,"threshold_uncertainty_score":0.1580153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2265055392948074,"score_gpt":0.533645390807665,"score_spread":0.3071398515128577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}