{"id":"W4402280882","doi":"10.7554/elife.100284","title":"Electrostatics of salt-dependent reentrant phase behaviors highlights diverse roles of ATP in biomolecular condensates","year":2024,"lang":"en","type":"article","venue":"eLife","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Electrostatics; Salt (chemistry); Reentrancy; Phase (matter); Chemical physics; Biophysics; Static electricity; Chemistry; Nanotechnology; Materials science; Condensed matter physics; Physics; Biology; Engineering; Electrical engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001067943,0.000128484,0.0001783999,0.00008463729,0.00001484911,0.000009281848,0.0001375002,0.0001194652,0.00001069406],"category_scores_gemma":[0.00002324123,0.0001138049,0.0000854919,0.0001140977,0.0001003517,0.000003516305,0.00006155521,0.00007451964,0.000001890185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001360426,"about_ca_system_score_gemma":0.00009004845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000511862,"about_ca_topic_score_gemma":0.00009537929,"domain_scores_codex":[0.9990739,0.00003216987,0.0002935572,0.0002275677,0.0001911965,0.0001815833],"domain_scores_gemma":[0.9995891,0.000009336879,0.00006746178,0.000223471,0.00006198844,0.00004864385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009296644,0.0000879588,0.0004446427,0.00005991161,0.00005123991,0.00005252044,0.0001921922,0.00002628653,0.9973168,0.0007041232,0.00008588052,0.000885449],"study_design_scores_gemma":[0.0006962302,0.0003953484,0.0001672509,0.00004240352,0.00004510085,0.0000106266,0.00006527636,0.0002663198,0.996717,0.0001428722,0.001329312,0.0001222056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929752,0.003527527,0.002999472,0.00006168401,0.0001016013,0.0001684357,0.0001192805,0.00001077763,0.00003604963],"genre_scores_gemma":[0.9987071,0.0004009847,0.0006079434,0.00004649858,0.00003692988,0.000006330712,0.0001245882,0.00001750771,0.00005215005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005731894,"threshold_uncertainty_score":0.4640829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005970251075977725,"score_gpt":0.2725812733843748,"score_spread":0.2666110223083971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}