{"id":"W4402363489","doi":"10.3390/pathogens13090776","title":"Inorganic Polyphosphate Is in the Surface of Trypanosoma cruzi but Is Not Significantly Secreted","year":2024,"lang":"en","type":"article","venue":"Pathogens","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; University of Georgia; National Institutes of Health; Kitasato University; University of Ottawa; American Heart Association","keywords":"Trypanosoma cruzi; Extracellular matrix; Myofibroblast; Cell biology; Polyphosphate; Secretion; Fibrosis; Biology; Transforming growth factor; Matrix metalloproteinase; Extracellular; Cardiac fibrosis; Chemistry; Biochemistry; Pathology; Parasite hosting; Medicine; Phosphate","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001389519,0.0002594194,0.0004446323,0.0001348817,0.00007335871,0.00004795799,0.000211147,0.0001609518,0.0008816902],"category_scores_gemma":[0.00008373931,0.0001916722,0.0002465483,0.0008723707,0.0001069819,0.0000933032,0.00004629657,0.0002450143,0.0001533145],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005210385,"about_ca_system_score_gemma":0.0002353025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004170373,"about_ca_topic_score_gemma":0.0000325656,"domain_scores_codex":[0.9980174,0.00008435668,0.0005532724,0.00044834,0.000495037,0.0004016422],"domain_scores_gemma":[0.9988942,0.0002623655,0.00009829835,0.0005348448,0.00009471866,0.0001156164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001505368,0.0001472952,0.0193032,0.0003154996,0.0001406407,0.0002799843,0.01348,0.000007230117,0.9568143,0.001170144,0.00366769,0.004523403],"study_design_scores_gemma":[0.001391051,0.0003584204,0.472562,0.000476622,0.0003766986,0.0001571647,0.002065316,0.004315663,0.506941,0.0005102068,0.01041681,0.0004290295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863492,0.007550239,0.00007561706,0.003485007,0.0003178327,0.0004871892,0.0003171467,0.0001085701,0.001309157],"genre_scores_gemma":[0.9946285,0.0003539369,0.0001782645,0.002398474,0.0001664747,0.00001079985,0.00004538954,0.00005312837,0.002165055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4532588,"threshold_uncertainty_score":0.965389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02544422908605266,"score_gpt":0.2739090374391297,"score_spread":0.248464808353077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}