{"id":"W4402363489","doi":"10.3390/pathogens13090776","title":"Inorganic Polyphosphate Is in the Surface of Trypanosoma cruzi but Is Not Significantly Secreted","year":2024,"lang":"en","type":"article","venue":"Pathogens","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; University of Georgia; National Institutes of Health; Kitasato University; University of Ottawa; American Heart Association","keywords":"Trypanosoma cruzi; Extracellular matrix; Myofibroblast; Cell biology; Polyphosphate; Secretion; Fibrosis; Biology; Transforming growth factor; Matrix metalloproteinase; Extracellular; Cardiac fibrosis; Chemistry; Biochemistry; Pathology; Parasite hosting; Medicine; Phosphate","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006494456,0.0003098291,0.000198041,0.0002451969,0.0001916444,0.0003044528,0.0001265117,0.000307487,0.001753055],"category_scores_gemma":[0.0002125326,0.0001175662,0.0002192298,0.0002385545,0.0001587733,0.0001843537,0.0001852222,0.0002489566,0.0007342306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001305901,"about_ca_system_score_gemma":0.000106283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004464032,"about_ca_topic_score_gemma":0.0004679206,"domain_scores_codex":[0.9998056,0.00002431094,0.0000146506,0.00004775023,0.00007723259,0.00003045526],"domain_scores_gemma":[0.9999028,0.00001864034,0.00003105481,0.000008858778,0.00001912142,0.00001952375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004790795,0.000007777351,0.0004600777,0.0000614585,0.00000383376,0.000119874,0.00001003564,0.00001241149,0.9981849,0.00003154968,0.0000361219,0.001024131],"study_design_scores_gemma":[0.00001284624,0.0004099928,0.02494692,0.00002183626,0.00003580868,0.003050164,0.00008886779,0.0007896647,0.9590975,0.00008845828,0.01144888,0.000009139398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859299,0.003915365,0.003684712,0.0001661978,0.00005412412,0.00004760235,0.001111646,0.00007576461,0.005014603],"genre_scores_gemma":[0.9858913,0.00136423,0.004869005,0.0001194882,0.00002378863,0.00004188183,0.003164917,0.0000262448,0.004499169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001753055,"threshold_uncertainty_score":0.005864561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02544422908605266,"score_gpt":0.2739090374391297,"score_spread":0.248464808353077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}