{"id":"W4402377315","doi":"10.1002/adtp.202400185","title":"Enhanced Targeted Drug Delivery for Scar Prevention: Clathrin‐Coated Solid Lipid Nanoparticles for Model Drug Encapsulation","year":2024,"lang":"en","type":"article","venue":"Advanced Therapeutics","topic":"Bee Products Chemical Analysis","field":"Agricultural and Biological Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Encapsulation (networking); Drug; Drug delivery; Solid lipid nanoparticle; Nanoparticle; Nanotechnology; Targeted drug delivery; Pharmacology; Chemistry; Materials science; Medicine; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002232931,0.0002206412,0.0002501691,0.00002074569,0.0002264964,0.00008892336,0.000221731,0.00008816302,0.00003785529],"category_scores_gemma":[0.00002812545,0.0001060745,0.0002667628,0.0004426627,0.00005694785,0.0003401994,0.00004072662,0.0001032455,0.00001236696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005571899,"about_ca_system_score_gemma":0.00002225815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004769264,"about_ca_topic_score_gemma":0.00007719468,"domain_scores_codex":[0.9984374,0.00003451891,0.0003732542,0.0005515777,0.0001829167,0.0004203104],"domain_scores_gemma":[0.9991913,0.000283407,0.0000964487,0.0001062804,0.0002419886,0.00008053568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008807865,0.00006360179,0.000003559388,0.00003003885,0.00007854642,1.189544e-7,0.0001343865,0.002433802,0.8099383,0.0003261899,0.00004965731,0.1868537],"study_design_scores_gemma":[0.0002329504,0.00007996029,0.00002131531,0.00004211254,0.0001401857,4.283337e-7,0.00009263332,0.1370895,0.8255244,0.02326025,0.01326891,0.0002473207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888946,0.002458038,0.004898064,0.002378951,0.0002196525,0.0007308963,0.0001048205,0.0002887468,0.00002626666],"genre_scores_gemma":[0.9914676,0.0003107815,0.005717771,0.0002467555,0.0003212473,0.0002160282,0.0002923028,0.000006954609,0.001420575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1866064,"threshold_uncertainty_score":0.4325591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02794068747145632,"score_gpt":0.2772263901841075,"score_spread":0.2492857027126512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}