{"id":"W4402438618","doi":"10.7554/elife.93117.2.sa0","title":"Author response: UGGT1-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Core Research for Evolutional Science and Technology; Canadian Glycomics Network; Biosignal Research Center, Kobe University; Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Glycan; Glycoprotein; Degradation (telecommunications); Cell biology; Chemistry; Biology; Computer science; Biochemistry; Telecommunications","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002256988,0.0007150106,0.0007369856,0.001057426,0.0008993388,0.002726074,0.0008431235,0.002559434,0.2193581],"category_scores_gemma":[0.01791541,0.000254434,0.0003175267,0.0006805271,0.0007379052,0.001528217,0.001563146,0.001846755,0.1237865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001046299,"about_ca_system_score_gemma":0.002737196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001094852,"about_ca_topic_score_gemma":0.002889361,"domain_scores_codex":[0.9978282,0.0003484119,0.0001543734,0.0003056028,0.001160014,0.0002033371],"domain_scores_gemma":[0.9839331,0.002121297,0.0007632376,0.000675418,0.0100755,0.002431478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001721389,0.00001833008,0.0003807544,0.0006085074,0.00001496607,0.0002827107,0.0001257203,0.00008176742,0.00371534,0.000718899,0.9554906,0.03839019],"study_design_scores_gemma":[0.00001907458,0.00003188325,0.0007117001,0.00008791461,0.000007083145,0.0001404492,0.0001995895,0.00008643862,0.001709372,0.0003183262,0.9966747,0.00001352614],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"commentary","genre_scores_codex":[0.01406882,0.01526289,0.006511109,0.2636814,0.5321869,0.0009707516,0.005782234,0.003739923,0.1577961],"genre_scores_gemma":[0.02932737,0.008968094,0.003144621,0.02116969,0.03666272,0.0001965469,0.003217116,0.001287704,0.8960261],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.2193581,"threshold_uncertainty_score":0.7338259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02403608842517783,"score_gpt":0.3109327797404586,"score_spread":0.2868966913152807,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}