{"id":"W4402453893","doi":"10.1091/mbc.e24-07-0307","title":"The GTP-tubulin cap is not the determinant of microtubule end stability in cells","year":2024,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; University of Minnesota; McGill University; National Cancer Institute; National Institutes of Health; National Eye Institute; Vanderbilt University; National Institute of General Medical Sciences; American Heart Association","keywords":"Microtubule; Tubulin; Biology; GTP'; Cell biology; Cytoskeleton; Microtubule nucleation; Biophysics; Cell; Biochemistry; Cell cycle; Centrosome; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001029804,0.0002543685,0.0003593428,0.0002771111,0.0002307603,0.0007210383,0.0002024788,0.0004695822,0.001037334],"category_scores_gemma":[0.0002953105,0.0001759528,0.0001782591,0.000174319,0.0003297865,0.0003996559,0.0002274858,0.0005282487,0.0003969159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004770863,"about_ca_system_score_gemma":0.0002210905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001419005,"about_ca_topic_score_gemma":0.001606178,"domain_scores_codex":[0.9998555,0.00001206478,0.00001325723,0.00004789235,0.00005014315,0.00002108786],"domain_scores_gemma":[0.9997646,0.00006349691,0.0000598281,0.00003590851,0.00003144527,0.00004472865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000037039,0.000007958181,0.0002931959,0.0000110749,0.000002386236,0.00004142609,0.000008435394,0.00004977322,0.9990544,0.0001046476,0.00001619462,0.0003734802],"study_design_scores_gemma":[0.000003709522,0.00005828002,0.01226937,0.000003621269,0.000008039425,0.0001746159,0.0000198987,0.001212783,0.9853857,0.00007973899,0.0007798547,0.000004326097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930409,0.001090112,0.002890583,0.0001097594,0.00003126047,0.00001291493,0.0004214581,0.00008540274,0.002317605],"genre_scores_gemma":[0.9964468,0.0002753198,0.001244918,0.0000469655,0.000009466815,0.00001970322,0.0004665697,0.00002442028,0.001465835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001419005,"threshold_uncertainty_score":0.003470242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00592924780442313,"score_gpt":0.2331325217455233,"score_spread":0.2272032739411001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}