{"id":"W4402475068","doi":"10.1021/acs.organomet.4c00281","title":"Tantalum Catalyzed Hydroaminoalkylation Enables a Telescoping Catalytic Reaction Sequence for the Synthesis of Benzoannulated Indolizidines and Quinolizidines","year":2024,"lang":"en","type":"article","venue":"Organometallics","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Fakultät für Chemie und Pharmazie, Ludwig-Maximilians-Universität München; Natural Sciences and Engineering Research Council of Canada; University of British Columbia; Canada Research Chairs; École Polytechnique Fédérale de Lausanne","keywords":"Chemistry; Catalysis; Telescoping series; Sequence (biology); Tantalum; Organic chemistry; Combinatorial chemistry; Stereochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007924475,0.0003514892,0.000146722,0.00014029,0.0001252146,0.0001127931,0.000352187,0.0001677874,0.001404202],"category_scores_gemma":[0.00009946305,0.0001262541,0.0001780688,0.000106739,0.0001672207,0.000223538,0.0002052392,0.000332262,0.0006174166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000224717,"about_ca_system_score_gemma":0.0002092724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004732384,"about_ca_topic_score_gemma":0.001663625,"domain_scores_codex":[0.9999272,0.000006868522,0.0000067369,0.0000186193,0.00001784174,0.00002268276],"domain_scores_gemma":[0.999966,0.000003445001,0.00001154911,0.000005654952,0.000005698881,0.000007636985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005372868,0.00002910965,0.0001351715,0.0001488354,0.00001123058,0.0003209355,0.00005646973,0.0003573578,0.9887544,0.001161899,0.0002121481,0.008758679],"study_design_scores_gemma":[0.00001213555,0.0003251217,0.0006404206,0.000005604648,0.0000116416,0.0003681007,0.00001718475,0.0008972139,0.9919749,0.0001094515,0.005626953,0.00001130439],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.939303,0.002416485,0.03957571,0.0002079124,0.0001284739,0.00017687,0.0004489667,0.0005044499,0.01723819],"genre_scores_gemma":[0.9875931,0.001102124,0.007948878,0.00003427836,0.00001444302,0.00002981153,0.0001548852,0.000026448,0.003096104],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001404202,"threshold_uncertainty_score":0.004697502,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03814079504897581,"score_gpt":0.2900801468863599,"score_spread":0.2519393518373841,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}