{"id":"W4402485661","doi":"10.3390/microorganisms12091880","title":"Diversification of Pseudomonas aeruginosa Biofilm Populations under Repeated Phage Exposures Decreases the Efficacy of the Treatment","year":2024,"lang":"en","type":"article","venue":"Microorganisms","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Aase og Ejnar Danielsens Fond; Bundesministerium für Bildung und Forschung; European Commission","keywords":"Pseudomonas aeruginosa; Microbiology; Biofilm; Diversification (marketing strategy); Biology; Bacteria; Genetics; Business","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000253034,0.0003886264,0.0007073552,0.0001807237,0.0002046917,0.000481344,0.0002165261,0.0006938795,0.001447306],"category_scores_gemma":[0.0006400879,0.0001892065,0.0003356081,0.0001358549,0.0002184261,0.0002436764,0.0004057527,0.0007694117,0.0003597385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001647001,"about_ca_system_score_gemma":0.0002127968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004477985,"about_ca_topic_score_gemma":0.0003694776,"domain_scores_codex":[0.9995413,0.0001057879,0.00002827666,0.0001027242,0.0001470038,0.00007499787],"domain_scores_gemma":[0.9995783,0.0001263789,0.00007150527,0.00006195132,0.00008163229,0.00008029491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009705509,0.00004138052,0.0003813941,0.00003071396,0.000007763203,0.00001912145,0.00002704582,0.00003271758,0.9978592,0.000008163677,0.00002157032,0.001473862],"study_design_scores_gemma":[0.00002197706,0.002186196,0.04651716,0.00001853975,0.00004427282,0.0003216445,0.0001043718,0.001037303,0.9480081,0.00004845919,0.001673571,0.0000184723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997207,0.00125648,0.0009532217,0.00006397772,0.00002318034,0.00002157489,0.00006452853,0.00002928468,0.0003807263],"genre_scores_gemma":[0.9975742,0.0003806474,0.001056172,0.00006724351,0.00001770373,0.00003852513,0.0001303251,0.00001624993,0.0007189803],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001447306,"threshold_uncertainty_score":0.004841745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01943135777075846,"score_gpt":0.252131129955162,"score_spread":0.2326997721844035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}