{"id":"W4402499059","doi":"10.1186/s12883-024-03847-1","title":"Pharmacological and physiological effects of cannabidiol: a dose escalation, placebo washout study protocol","year":2024,"lang":"en","type":"article","venue":"BMC Neurology","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia, Okanagan Campus; University of British Columbia; Saskatchewan Health Authority; University of Regina; Genome Prairie; University of Saskatchewan; Saskatchewan Health; Canadian Rural Health Research Society","funders":"Mitacs; National Football League Players Association; University of Regina","keywords":"Cannabidiol; Medicine; Population; Dosing; Neurology; Anxiety; Regimen; Placebo; Anesthesia; Pharmacology; Internal medicine; Cannabis; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003052462,0.0001736693,0.0004013699,0.0001411491,0.00004904378,0.00001757486,0.00009387617,0.0001457529,0.0001627787],"category_scores_gemma":[0.0002699983,0.0001143982,0.00009400569,0.0002492136,0.0002491927,0.00003544864,0.000160664,0.0004623712,0.00001567906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001669851,"about_ca_system_score_gemma":0.0001880927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002176245,"about_ca_topic_score_gemma":0.00001117544,"domain_scores_codex":[0.9982361,0.0003938356,0.0002855326,0.0005106236,0.0002530076,0.0003209611],"domain_scores_gemma":[0.9994079,0.0001095618,0.00003756108,0.0001857298,0.00008265521,0.0001765605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.02848439,0.006663922,0.2994084,0.007333805,0.0005061669,0.00380221,0.001228611,0.00009083476,0.4917169,0.0009504793,0.1349674,0.02484687],"study_design_scores_gemma":[0.008031381,0.01473374,0.9460453,0.00003746105,0.000176687,0.0003026319,0.00002779614,0.002336718,0.00475627,0.0001939455,0.02318184,0.0001762608],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9323235,0.00009996815,0.00002213473,0.002050648,0.000144056,0.06504636,0.00000242705,0.000103513,0.0002073997],"genre_scores_gemma":[0.9332484,0.000007188633,0.0000209231,0.0004150163,0.0002173067,0.06509168,0.000002267794,0.0000208355,0.000976411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6466368,"threshold_uncertainty_score":0.4665022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03729808989863218,"score_gpt":0.3837248488510709,"score_spread":0.3464267589524387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}