{"id":"W4402499383","doi":"10.1186/s40364-024-00634-5","title":"Updates on CAR T cell therapy in multiple myeloma","year":2024,"lang":"en","type":"review","venue":"Biomarker Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Chimeric antigen receptor; Medicine; Cytokine release syndrome; Immunotherapy; Multiple myeloma; T cell; Cancer research; Immunology; Cancer; Oncology; Internal medicine; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007891723,0.0005045232,0.0008134996,0.001168907,0.0002017771,0.0009124355,0.0006399237,0.001040126,0.0045986],"category_scores_gemma":[0.0008921071,0.0002151352,0.0006599969,0.000947559,0.0002382617,0.001103579,0.0005081333,0.00209108,0.001918213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004543466,"about_ca_system_score_gemma":0.0006732884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006224678,"about_ca_topic_score_gemma":0.001122578,"domain_scores_codex":[0.9997789,0.00004896662,0.00003602764,0.00003374976,0.00007225205,0.00003017393],"domain_scores_gemma":[0.9995458,0.0002433676,0.00004394707,0.00001101502,0.0001159245,0.00003997147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002050337,0.0001079222,0.0001531542,0.009850327,0.00009035478,0.0002226545,0.00007739422,0.0005945594,0.003992795,0.002870599,0.0634182,0.9184169],"study_design_scores_gemma":[0.00003273435,0.0002416871,0.0003398928,0.001677474,0.0001151165,0.0005989817,0.00002249385,0.0001139603,0.0009988752,0.0006239952,0.9952222,0.00001259314],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005183758,0.9948761,0.0003703577,0.0009045516,0.0008759694,0.00001395598,0.00007150162,0.00002918112,0.002340001],"genre_scores_gemma":[0.002281678,0.9927441,0.000562781,0.001460888,0.001081863,0.00002585409,0.0002022405,0.000009315178,0.001631372],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0045986,"threshold_uncertainty_score":0.01538378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3086141038793038,"score_gpt":0.48950730688676,"score_spread":0.1808932030074563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}