{"id":"W4402507657","doi":"10.1021/acsptsci.4c00292","title":"Development of Pro-resolving and Pro-efferocytic Nanoparticles for Atherosclerosis Therapy","year":2024,"lang":"en","type":"article","venue":"ACS Pharmacology & Translational Science","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University; Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Research, Innovation and Science; Ottawa Hospital Research Institute; Institute of Circulatory and Respiratory Health; University of Ottawa","keywords":"Nanotechnology; Medicine; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006349172,0.0001010076,0.0001393055,0.0001046921,0.0003716902,0.00002165168,0.0001516467,0.00006628664,0.00003711752],"category_scores_gemma":[0.00001367142,0.00008300249,0.00004036076,0.000203346,0.0004981785,0.0002293759,0.00001806405,0.00005728297,0.000004245436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002924261,"about_ca_system_score_gemma":0.0003184147,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001631361,"about_ca_topic_score_gemma":0.000001640531,"domain_scores_codex":[0.9991112,0.00002905463,0.0002652654,0.0002900533,0.00005418459,0.0002502847],"domain_scores_gemma":[0.9995092,0.0002719005,0.00004950526,0.0000515314,0.00009995307,0.00001796995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001083565,0.00005470492,0.0002560695,0.00004087765,0.0000683423,3.058312e-8,0.001545502,0.0000204079,0.9519206,0.00176085,0.00006261501,0.04416167],"study_design_scores_gemma":[0.001075025,0.00009996706,0.01555043,0.00002933726,0.00003258358,0.000003565677,0.00002716267,0.0007907026,0.9713668,0.0003798236,0.01055051,0.00009406055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905124,0.00533731,0.002374349,0.0005369164,0.0004039512,0.0007634919,0.00001986223,0.0000350485,0.00001662789],"genre_scores_gemma":[0.9959822,0.00007176754,0.003527434,0.00006759409,0.0000212968,0.0002541321,0.00001907541,0.000008345279,0.00004812749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04406761,"threshold_uncertainty_score":0.3384744,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05309654846506463,"score_gpt":0.3293311306791555,"score_spread":0.2762345822140909,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}