{"id":"W4402509742","doi":"10.1016/j.clim.2024.110364","title":"High symptom burden in female X-linked chronic granulomatous disease carriers","year":2024,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Hospital for Sick Children","funders":"NHLBI Division of Intramural Research; National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Cancer Institute; Health Resources and Services Administration; Office of Naval Research; National Heart, Lung, and Blood Institute","keywords":"Chronic granulomatous disease; Medicine; Granulomatous disease; Burden of disease; Disease; Disease burden; Dermatology; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001553623,0.0003634944,0.000310844,0.0009102556,0.0004608371,0.0005494329,0.0002005243,0.000543919,0.00577849],"category_scores_gemma":[0.001720188,0.0001702108,0.0001378972,0.0005542142,0.0002993622,0.0003603787,0.00029047,0.0002874005,0.0005320254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001092101,"about_ca_system_score_gemma":0.0001510068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001140529,"about_ca_topic_score_gemma":0.000700858,"domain_scores_codex":[0.9998329,0.00004162163,0.00001170857,0.00003790824,0.00003038947,0.0000454418],"domain_scores_gemma":[0.9992938,0.0001882962,0.0002789219,0.00002761219,0.00003905259,0.0001723568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003559708,0.00005856279,0.9850515,0.00002133202,0.00001850272,0.005595298,0.0002466416,0.00003348337,0.00473295,0.00006501286,0.0003281457,0.003492695],"study_design_scores_gemma":[0.000005955777,0.0001730229,0.9887741,0.000009797668,0.00001794999,0.009964482,0.0004354214,0.00009428488,0.0001752293,0.00005704983,0.0002873699,0.000005406604],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986821,0.000246104,0.00005072463,0.00009374254,0.000007927254,0.000003504027,0.0001383014,0.000005865253,0.0007716976],"genre_scores_gemma":[0.9995279,0.00008980702,0.00002349199,0.00002000547,0.00001725342,0.000002249158,0.00007678042,0.000002207707,0.0002402675],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00577849,"threshold_uncertainty_score":0.01933098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02357210895572626,"score_gpt":0.3059498264318285,"score_spread":0.2823777174761022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}