{"id":"W4402512836","doi":"10.46747/cfp.7009537","title":"Potential of anti-amyloid therapies for patients with Alzheimer disease in Canada","year":2024,"lang":"en","type":"article","venue":"Canadian Family Physician","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; Queen's University; Élisabeth Bruyère Hospital","funders":"","keywords":"Disease; Medicine; Amyloid (mycology); Alzheimer's disease; Amyloid β; Bioinformatics; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008297146,0.00027474,0.0004296565,0.0008269984,0.003683901,0.001963298,0.0010602,0.0009124242,0.01447495],"category_scores_gemma":[0.002283294,0.0001442499,0.0005912681,0.00132451,0.0007024877,0.0005457774,0.0007767958,0.001652412,0.0006662193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.03890603,"about_ca_system_score_gemma":0.1398747,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9796168,"about_ca_topic_score_gemma":0.9948713,"domain_scores_codex":[0.9991698,0.0001083681,0.00004176507,0.00004703993,0.0003731554,0.0002598447],"domain_scores_gemma":[0.9970493,0.0001473266,0.0001482341,0.00001880696,0.001610358,0.001026046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001886706,0.0007722559,0.07846584,0.001653323,0.0002599427,0.001684658,0.001012352,0.001085904,0.001715681,0.02218604,0.3644936,0.5247837],"study_design_scores_gemma":[0.001579808,0.0009634987,0.2276066,0.004115817,0.0009003774,0.001980739,0.003750009,0.002273456,0.001366841,0.006683145,0.7486146,0.0001650086],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.1320453,0.2131492,0.001166362,0.3483525,0.003556012,0.0005259187,0.008132529,0.0002313431,0.2928408],"genre_scores_gemma":[0.7405612,0.1758345,0.004914479,0.04058341,0.001777143,0.0002061246,0.002941734,0.00006069804,0.03312067],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.03890603,"threshold_uncertainty_score":0.2822844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01308343651449628,"score_gpt":0.2434624424109846,"score_spread":0.2303790058964883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}