{"id":"W4402515724","doi":"10.1039/d4sc03594a","title":"Discovery of megapolipeptins by genome mining of a <i>Burkholderiales</i> bacteria collection","year":2024,"lang":"en","type":"article","venue":"Chemical Science","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of New Brunswick; Simon Fraser University","funders":"National Center for Complementary and Integrative Health; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Genome; Computational biology; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004201517,0.0007581023,0.0007240853,0.001170587,0.0004327975,0.00154447,0.0004140222,0.0005100029,0.00131184],"category_scores_gemma":[0.001080568,0.0002755903,0.0007481916,0.001977547,0.0002160386,0.0005536376,0.0007837344,0.001016524,0.001185499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000344196,"about_ca_system_score_gemma":0.0007219951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001882068,"about_ca_topic_score_gemma":0.003118715,"domain_scores_codex":[0.9996796,0.0000293548,0.00003211517,0.00009437481,0.0001183072,0.00004627072],"domain_scores_gemma":[0.9994948,0.0001096763,0.000130295,0.00007088802,0.00010616,0.00008806303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005204215,0.0001203994,0.01748074,0.0007804061,0.0001813816,0.0008133076,0.0002323001,0.0009883054,0.9368567,0.0003743922,0.001795348,0.03985619],"study_design_scores_gemma":[0.0001213108,0.000831097,0.1300796,0.0003955189,0.0006723108,0.005695425,0.001035896,0.007553151,0.7576876,0.001315096,0.09448216,0.0001308608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9009327,0.006326559,0.02343475,0.0008948483,0.00008129644,0.0002663229,0.06146004,0.001654447,0.004948943],"genre_scores_gemma":[0.8262226,0.003967103,0.06279609,0.0003901572,0.0000379631,0.0001733685,0.1039044,0.0004691805,0.002039252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001882068,"threshold_uncertainty_score":0.004388511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01129734615337911,"score_gpt":0.2295803340994171,"score_spread":0.218282987946038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}