{"id":"W4402526304","doi":"10.3390/v16091456","title":"Coxsackievirus B3 Activates Macrophages Independently of CAR-Mediated Viral Entry","year":2024,"lang":"en","type":"article","venue":"Viruses","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; St. Paul's Foundation","keywords":"Coxsackievirus; Enterovirus; Viral replication; Viral entry; Innate immune system; Virology; Biology; Viral pathogenesis; Macrophage; Virus; Immunology; Immune system; Enterovirus 71; Chemokine; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002825829,0.0004088818,0.0002415801,0.0001939134,0.0001812813,0.0003917451,0.0001488339,0.0003027897,0.001499025],"category_scores_gemma":[0.0001277684,0.0001218542,0.0004437628,0.0001167783,0.0002908194,0.0002747311,0.0003667802,0.000640653,0.000521775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000264163,"about_ca_system_score_gemma":0.0003446719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006862856,"about_ca_topic_score_gemma":0.0009584547,"domain_scores_codex":[0.9997191,0.00007150981,0.0000186415,0.00003473828,0.00004943345,0.0001066592],"domain_scores_gemma":[0.9999124,0.00002232457,0.00001671663,0.00001495541,0.00001409531,0.00001956588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003270408,0.00005340653,0.0003257456,0.00007219972,0.000005659419,0.00007920957,0.00003317093,0.00003435531,0.9975544,0.0002874739,0.00006556072,0.00116174],"study_design_scores_gemma":[0.0000909474,0.0007184317,0.00965385,0.0000240361,0.00001902457,0.0006302847,0.0001590952,0.001419288,0.9819386,0.0002773542,0.005059686,0.00000946376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911573,0.002079398,0.003090886,0.0001972244,0.00005248386,0.0000556774,0.0003150813,0.00007427559,0.002977795],"genre_scores_gemma":[0.994593,0.0007742565,0.00171992,0.0001089643,0.0000143724,0.00005820916,0.0002470243,0.0000122488,0.002471918],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001499025,"threshold_uncertainty_score":0.005014718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03100302171292517,"score_gpt":0.3458176288736102,"score_spread":0.314814607160685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}