{"id":"W4402544026","doi":"10.1093/pch/pxae029","title":"Gene-based drug therapy for children and youth treated with psychoactive medications","year":2024,"lang":"en","type":"article","venue":"Paediatrics & Child Health","topic":"Attention Deficit Hyperactivity Disorder","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Paediatric Society","funders":"","keywords":"Psychoactive drug; Drug; Medicine; Pharmacotherapy; Psychoactive substance; Psychiatry; Pharmacology; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003861499,0.0001518367,0.0003049466,0.0004339242,0.0004339034,0.0004594031,0.0003056067,0.0005503238,0.005069816],"category_scores_gemma":[0.00181542,0.00005755349,0.0005116225,0.0003613519,0.0003477618,0.0002711748,0.0005909838,0.0008709418,0.0007046078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001034164,"about_ca_system_score_gemma":0.001250165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002978491,"about_ca_topic_score_gemma":0.007025703,"domain_scores_codex":[0.9997003,0.00008468824,0.00003018092,0.00003525947,0.00009885585,0.00005074647],"domain_scores_gemma":[0.9994641,0.0001610614,0.0001334581,0.00002309118,0.00007291684,0.0001454518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0007916975,0.0007781188,0.1591441,0.001458476,0.0002098046,0.008017529,0.0009008909,0.0004952455,0.005429962,0.006799834,0.06583685,0.7501374],"study_design_scores_gemma":[0.000800645,0.002922263,0.3802063,0.007078624,0.0007461348,0.04020204,0.001753226,0.001498748,0.01114062,0.009775617,0.5437898,0.00008592346],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5785576,0.1965737,0.008846815,0.08819616,0.002557531,0.0006993266,0.00450244,0.0009914819,0.119075],"genre_scores_gemma":[0.8822941,0.07360406,0.01592565,0.01314795,0.0007471329,0.0003963519,0.001469576,0.00008808555,0.01232701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005069816,"threshold_uncertainty_score":0.01696026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02193640119013986,"score_gpt":0.3219439999704886,"score_spread":0.3000075987803487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}