{"id":"W4402545884","doi":"10.1515/hsz-2024-0088","title":"The BCL11A transcription factor stimulates the enzymatic activities of the OGG1 DNA glycosylase","year":2024,"lang":"en","type":"article","venue":"Biological Chemistry","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"DNA glycosylase; Zinc finger; Gene knockdown; Chemistry; Uracil-DNA glycosylase; DNA; Biochemistry; Transcription factor; Molecular biology; Transcription (linguistics); DNA repair; Gene; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001034362,0.0004106277,0.0001807544,0.0002111994,0.0001761408,0.0003112054,0.00009352499,0.0002470698,0.002276398],"category_scores_gemma":[0.0001330799,0.0001165701,0.0002347859,0.0001174132,0.0001862046,0.0001783463,0.0002866788,0.0005730352,0.00066491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003859609,"about_ca_system_score_gemma":0.0001315118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006500602,"about_ca_topic_score_gemma":0.0008406222,"domain_scores_codex":[0.9998422,0.00002341205,0.00001050695,0.00003944905,0.00004459986,0.00003983808],"domain_scores_gemma":[0.9998197,0.000037114,0.00004691801,0.00001584579,0.00001938364,0.00006094301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006333469,0.00001703478,0.000266748,0.00002101535,0.000002123265,0.0000209477,0.000006676593,0.00001954899,0.9987418,0.00002933459,0.00002883825,0.0007826137],"study_design_scores_gemma":[0.0000193578,0.0002339067,0.008012461,0.000006503491,0.000007899956,0.0001595962,0.00002819604,0.0005921933,0.987289,0.00003885755,0.003607192,0.000005031133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911458,0.002358746,0.003216754,0.0001957746,0.00005180921,0.00002980537,0.0003720461,0.00009360704,0.00253564],"genre_scores_gemma":[0.992994,0.0006778294,0.001627637,0.00007777436,0.0000106949,0.00002654764,0.0005663671,0.00001720546,0.004001969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002276398,"threshold_uncertainty_score":0.007615268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01594290396354334,"score_gpt":0.2378561682904606,"score_spread":0.2219132643269173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}