{"id":"W4402547787","doi":"10.1007/s00285-024-02138-0","title":"Graph-based, dynamics-preserving reduction of (bio)chemical systems","year":2024,"lang":"en","type":"article","venue":"Journal of Mathematical Biology","topic":"Gene Regulatory Network Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; University of Lethbridge","keywords":"Reduction (mathematics); Mathematics; Graph; Dynamics (music); Theoretical computer science; Computer science; Biological system; Discrete mathematics; Biology; Physics; Geometry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006132665,0.0001303805,0.0003675522,0.0001570654,0.00001857392,0.00001783656,0.0002523386,0.0002405428,0.00004021662],"category_scores_gemma":[0.0001548183,0.00009732915,0.000339461,0.0001860732,0.000164226,0.00000440196,0.00006636894,0.0001543325,0.000005805247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003137944,"about_ca_system_score_gemma":0.00008826068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001706628,"about_ca_topic_score_gemma":6.293381e-7,"domain_scores_codex":[0.9987247,0.0001292279,0.000653577,0.0001780678,0.0001374259,0.0001769857],"domain_scores_gemma":[0.9991764,0.0000653281,0.0002419754,0.0002518525,0.0001775497,0.0000868792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008795412,0.0001268984,0.0003216702,0.0004544994,0.0005298693,0.00001125809,0.00002342627,0.001486102,0.9830625,0.01034052,0.002298821,0.001256485],"study_design_scores_gemma":[0.001633635,0.002561919,0.000131276,0.001566207,0.001488444,0.003253349,0.0007302737,0.1681478,0.742948,0.06727097,0.009277954,0.000990128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9212046,0.005442516,0.07215975,0.0003534836,0.0004296711,0.00008039244,0.000008753501,0.000008951389,0.0003118937],"genre_scores_gemma":[0.9963589,0.00007665763,0.003018273,0.00001010632,0.0004140365,0.000002778525,0.00002159737,0.00001691818,0.00008074012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2401145,"threshold_uncertainty_score":0.3968968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01010977930775782,"score_gpt":0.2585284779761892,"score_spread":0.2484186986684314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}