{"id":"W4402557297","doi":"10.1111/dom.15957","title":"Do nonglycaemic effects such as weight loss account for <scp>HbA1c</scp> lowering with efpeglenatide?: Insights from the <scp>AMPLITUDE‐</scp> O trial","year":2024,"lang":"en","type":"letter","venue":"Diabetes Obesity and Metabolism","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; McMaster University; Population Health Research Institute","funders":"Sanofi","keywords":"Medicine; Weight loss; Food science; Internal medicine; Obesity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005113713,0.0006063079,0.002213304,0.0002709624,0.0002472569,0.001329903,0.0007975363,0.001782459,0.005277893],"category_scores_gemma":[0.008201005,0.0002772612,0.003353764,0.0004841187,0.0007047276,0.001291416,0.0005057718,0.001852331,0.0005385194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005250951,"about_ca_system_score_gemma":0.0008761837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001210238,"about_ca_topic_score_gemma":0.002448371,"domain_scores_codex":[0.998769,0.0006603684,0.0001371316,0.0001148237,0.0001790059,0.0001396639],"domain_scores_gemma":[0.9962918,0.00214746,0.0008859903,0.0002654564,0.0001524385,0.0002569067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3386175,0.002051529,0.08471845,0.008426555,0.02146307,0.0009718013,0.0002852147,0.001962723,0.003778962,0.007743363,0.01452126,0.5154595],"study_design_scores_gemma":[0.2472695,0.04098591,0.4574498,0.006498164,0.07767291,0.003525636,0.001200818,0.02260348,0.004224225,0.06241853,0.07575595,0.0003950809],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6464667,0.2886475,0.003390871,0.03230523,0.001872451,0.00108032,0.002855465,0.0001161067,0.02326531],"genre_scores_gemma":[0.9388739,0.04313641,0.001710435,0.01012201,0.002270813,0.0003683955,0.001507018,0.00005892335,0.001952111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005277893,"threshold_uncertainty_score":0.02704418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008594574529834389,"score_gpt":0.2268797056877815,"score_spread":0.2182851311579471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}