{"id":"W4402558028","doi":"10.1002/app.56278","title":"Tailoring N, N, N‐trimethyl chitosan nanospheres as an efficient drug carrier to overcome endothelial barrier","year":2024,"lang":"en","type":"article","venue":"Journal of Applied Polymer Science","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chitosan; Materials science; Drug; Drug carrier; Nanotechnology; Drug delivery; Chemical engineering; Chemistry; Organic chemistry; Medicine; Pharmacology; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002146824,0.0003117397,0.0004052666,0.0005345796,0.000421682,0.0009793488,0.00152474,0.00006222676,0.0005910302],"category_scores_gemma":[0.00008129206,0.0002484998,0.000146346,0.001602398,0.0006053359,0.0009435653,0.0003059742,0.0003472505,0.0004119804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001895794,"about_ca_system_score_gemma":0.001476426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001204246,"about_ca_topic_score_gemma":0.000005816666,"domain_scores_codex":[0.995603,0.00007159089,0.0007973362,0.0007032129,0.001938207,0.0008866939],"domain_scores_gemma":[0.9978517,0.0001802967,0.0002340092,0.0005770426,0.0001479624,0.001009045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002132069,0.00008172779,0.0000288414,0.0000150517,0.000009264801,0.00009037735,0.003166073,0.001371158,0.9881971,0.003317024,0.0002035772,0.003306595],"study_design_scores_gemma":[0.0003746128,0.0002177117,0.0000964761,0.00008396562,0.00003991892,0.00009718409,0.0006445218,0.0005730618,0.9961787,0.0002538877,0.001120481,0.0003194688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917912,0.001263706,0.000194246,0.0004143176,0.003685039,0.0002374786,0.00003478382,0.000100425,0.002278727],"genre_scores_gemma":[0.9968002,0.000006519867,0.001571648,0.0006595901,0.0007289303,0.00001205715,2.457816e-7,0.00004047138,0.0001803475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007981607,"threshold_uncertainty_score":0.9999967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008061303824140312,"score_gpt":0.2551205197586061,"score_spread":0.2470592159344658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}