{"id":"W4402558343","doi":"10.1016/j.annonc.2024.08.1361","title":"1304P Investigator-initiated study of crizotinib in patients with MET activated advanced stage non-small cell lung cancer: A Canadian experience","year":2024,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Princess Margaret Cancer Foundation; AstraZeneca; EMD Serono; Pfizer; Amgen","keywords":"Crizotinib; Medicine; Stage (stratigraphy); Lung cancer; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001325096,0.0006141216,0.001151566,0.0002240798,0.001153341,0.001235668,0.0007979653,0.0006730568,0.001750132],"category_scores_gemma":[0.001375296,0.0002364309,0.0008584764,0.001189528,0.0008020756,0.0004217204,0.0003495041,0.002050615,0.0003421831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0170266,"about_ca_system_score_gemma":0.01874229,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.5428501,"about_ca_topic_score_gemma":0.8119814,"domain_scores_codex":[0.9991698,0.0002105019,0.00002359978,0.0001117616,0.0002651676,0.0002192187],"domain_scores_gemma":[0.9988951,0.0000892476,0.0001160216,0.00003551928,0.0003117467,0.0005524443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1384942,0.00827614,0.2579041,0.001261183,0.002802756,0.00505337,0.003216343,0.006206922,0.04880253,0.006457225,0.1061244,0.4154009],"study_design_scores_gemma":[0.09072854,0.04365302,0.6680508,0.0005581615,0.002398718,0.004489013,0.001835068,0.004695037,0.004020379,0.002261021,0.1769497,0.0003605821],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9324017,0.01601685,0.001071424,0.01005695,0.0004291362,0.00126619,0.00707033,0.00005505504,0.03163231],"genre_scores_gemma":[0.9721403,0.009200839,0.002489543,0.00353567,0.0002405113,0.0002783633,0.006005669,0.0000814155,0.006027751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4571499,"threshold_uncertainty_score":0.9196842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04988997537621109,"score_gpt":0.4081307226466593,"score_spread":0.3582407472704482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}