{"id":"W4402559952","doi":"10.1016/j.annonc.2024.08.796","title":"734P Impact of investigator-assessed response on overall survival (OS) in patients (pts) with primary advanced or recurrent endometrial cancer (pA/rEC) in the ENGOT-EN6-NSGO/GOG3031/RUBY trial","year":2024,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"National Cancer Institute; Genentech; Eisai; Seagen; MacroGenics; Moderna; Clovis Oncology; Incyte; Astellas Pharma; Novocure; Regeneron Pharmaceuticals; Gilead Sciences; EMD Serono; Mersana Therapeutics; Bristol-Myers Squibb; AstraZeneca; Amgen; Pfizer","keywords":"Medicine; Endometrial cancer; Overall survival; Oncology; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002012118,0.0004253882,0.001204574,0.0001590769,0.0001936405,0.0008009853,0.000349321,0.0009098233,0.008796812],"category_scores_gemma":[0.002165114,0.000164084,0.001847864,0.0003442147,0.000423343,0.0006075074,0.0002713098,0.002106252,0.0009756372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005206956,"about_ca_system_score_gemma":0.000506417,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006759037,"about_ca_topic_score_gemma":0.00228548,"domain_scores_codex":[0.9991504,0.0005824055,0.00003868508,0.00007404759,0.00005207514,0.0001023451],"domain_scores_gemma":[0.9992033,0.0003862783,0.0001501172,0.00006924816,0.0000474699,0.000143625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8556384,0.0010263,0.01258403,0.001103145,0.00457584,0.0001508766,0.00006756975,0.001844991,0.003967623,0.0006835273,0.01086026,0.1074975],"study_design_scores_gemma":[0.6304342,0.1477255,0.1709741,0.0005524834,0.01182221,0.0004852242,0.000215233,0.005486822,0.00308666,0.004681677,0.02442425,0.0001116706],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9627891,0.0111845,0.0006180019,0.003565283,0.0006029833,0.0004434868,0.006017749,0.0001671935,0.01461169],"genre_scores_gemma":[0.9913015,0.001239837,0.0003718614,0.001256523,0.0002417445,0.000257177,0.002022581,0.00002964387,0.003279144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008796812,"threshold_uncertainty_score":0.02942824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1182615050728911,"score_gpt":0.4374177670860609,"score_spread":0.3191562620131698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}