{"id":"W4402565641","doi":"10.1016/j.annonc.2024.08.2230","title":"226TiP CLEAR-Me: Interception trial to detect and clear molecular residual disease in patients with high-risk melanoma","year":2024,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Cutaneous Melanoma Detection and Management","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Disease; Oncology; Internal medicine; Melanoma; Interception; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004240868,0.0005349891,0.0007071576,0.0001480247,0.0001680027,0.0007430859,0.0003406332,0.000498192,0.005928956],"category_scores_gemma":[0.0006638043,0.0002073053,0.0007153234,0.0001383877,0.0002294789,0.0005246624,0.0002594517,0.002083573,0.0007839414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003963917,"about_ca_system_score_gemma":0.0004130243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006920957,"about_ca_topic_score_gemma":0.002415819,"domain_scores_codex":[0.9998584,0.00005005738,0.000007618597,0.00002963489,0.00001739675,0.00003690979],"domain_scores_gemma":[0.9997541,0.00005858509,0.00005553166,0.00001987618,0.00001686551,0.00009488635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5418409,0.006980791,0.02928258,0.001668915,0.002864855,0.0003238249,0.0001538793,0.002885517,0.02069274,0.001266616,0.02177886,0.3702607],"study_design_scores_gemma":[0.5530952,0.2452428,0.1606292,0.0005488298,0.004117863,0.0009660488,0.0002546376,0.007180444,0.004676424,0.001798629,0.0213654,0.0001245404],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9799526,0.007692697,0.0004573976,0.001594275,0.0003563375,0.0003497849,0.0007960835,0.0001272834,0.008673592],"genre_scores_gemma":[0.9851084,0.002981004,0.0007586041,0.001384169,0.0003714573,0.0002313068,0.00151209,0.00003058978,0.007622435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005928956,"threshold_uncertainty_score":0.01983434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01854965998016122,"score_gpt":0.308266031979694,"score_spread":0.2897163719995328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}