{"id":"W4402574058","doi":"10.1111/all.16322","title":"Up‐dosing of reslizumab in severe asthmatics with persistent sputum eosinophilia: A feasibility study","year":2024,"lang":"en","type":"letter","venue":"Allergy","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Teva Canada Innovation","keywords":"Eosinophilia; Medicine; Dosing; Sputum; Immunology; Pediatrics; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003908401,0.001370702,0.001863073,0.0004102929,0.0005361563,0.001002534,0.001356388,0.001386161,0.003480043],"category_scores_gemma":[0.002436857,0.0009020633,0.001740011,0.0004385674,0.001278429,0.001274973,0.0006784216,0.002708901,0.0010962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009167944,"about_ca_system_score_gemma":0.002095071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001386796,"about_ca_topic_score_gemma":0.001853621,"domain_scores_codex":[0.9977362,0.001384554,0.0001314258,0.0001949623,0.0002213021,0.0003314751],"domain_scores_gemma":[0.9983478,0.0004853117,0.0003087069,0.0002205444,0.0001302424,0.0005074925],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5713757,0.2346302,0.01735207,0.001280369,0.001020733,0.001442418,0.0005877741,0.001517656,0.05784472,0.0003809325,0.001580989,0.1109865],"study_design_scores_gemma":[0.1226134,0.8564883,0.01637067,0.00004058942,0.0003340621,0.0003055745,0.00009252423,0.0006308678,0.001407229,0.00009587576,0.001591446,0.00002931855],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886035,0.001452133,0.001198518,0.0002910415,0.00007496707,0.006606843,0.0003099707,0.00004932898,0.001413793],"genre_scores_gemma":[0.9929888,0.001031495,0.001755915,0.0003906422,0.0001884397,0.002762794,0.0004160096,0.0000117899,0.0004542244],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003908401,"threshold_uncertainty_score":0.02066982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02944990789419298,"score_gpt":0.2805703267874243,"score_spread":0.2511204188932313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}