{"id":"W4402580541","doi":"10.1007/s13555-024-01258-1","title":"Impact of Disease Factors of Patients with Psoriasis and Psoriatic Arthritis on Biologic Therapy Switching: Real-World Evidence from the CorEvitas Psoriasis Registry","year":2024,"lang":"en","type":"article","venue":"Dermatology and Therapy","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Chugai Pharmaceutical; LEO Pharma; UCB Pharma; Regeneron Pharmaceuticals; Celgene; Eli Lilly and Company; Bristol-Myers Squibb; Ortho Dermatologics; Janssen Pharmaceuticals; UCB US; Gilead Sciences; Sanofi; Pfizer; Genentech; National Psoriasis Foundation; Amgen","keywords":"Psoriasis; Psoriatic arthritis; Medicine; Dermatology; Disease; Arthritis; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005071091,0.000228753,0.0004523243,0.0007614278,0.0003604261,0.001086366,0.0006698166,0.0004808724,0.001250806],"category_scores_gemma":[0.02129602,0.0003073625,0.001259533,0.001705994,0.0003115655,0.0006803958,0.0005385354,0.0009482228,0.0001509494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005612931,"about_ca_system_score_gemma":0.0009005531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01926848,"about_ca_topic_score_gemma":0.01869472,"domain_scores_codex":[0.995544,0.002173824,0.0004690999,0.0006661001,0.0008501483,0.0002969034],"domain_scores_gemma":[0.9730383,0.01026555,0.0115809,0.002467858,0.001641521,0.00100584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005365638,0.00003901125,0.995814,0.00004149982,0.0004006831,0.00001656887,0.00003457441,0.0000821669,0.0000155565,0.00002691526,0.0002282244,0.002764252],"study_design_scores_gemma":[0.00005189687,0.0001130522,0.9983582,0.00004510603,0.0002997779,0.00009341606,0.00008722919,0.0003675657,0.00002283357,0.00003529662,0.0005172222,0.000008298219],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911456,0.004146917,0.0002060308,0.0003090898,0.00003152358,0.00002693777,0.002964054,0.000007675469,0.00116211],"genre_scores_gemma":[0.996783,0.0008875226,0.0001171688,0.00008434733,0.0000317973,0.00001341345,0.002001811,0.000003105743,0.00007775475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01926848,"threshold_uncertainty_score":0.03831267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0255114006844872,"score_gpt":0.2718232195659058,"score_spread":0.2463118188814186,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}