{"id":"W4402589716","doi":"10.1055/a-2417-9450","title":"Efficient and Direct Route to 5-Iodo-4H-Quinoxalines via Copper-Catalyzed Double C–N Arylations of 1,2,3-Triiodoarenes: Potential Application towards 5-Substituted 4H-Quinoxalines","year":2024,"lang":"en","type":"article","venue":"Synthesis","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"Deanship of Research, Jordan University of Science and Technology","keywords":"Chemistry; Copper; Catalysis; Combinatorial chemistry; Organic chemistry; Medicinal chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000586022,0.0003353567,0.0005220268,0.0002003546,0.0001755535,0.0001112965,0.0002782059,0.0002693818,0.0004819174],"category_scores_gemma":[0.0004941031,0.0002623496,0.0001983929,0.0005346394,0.0001489835,0.00008383371,0.0001263408,0.0001115305,0.00009447825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009585333,"about_ca_system_score_gemma":0.00009584466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007094798,"about_ca_topic_score_gemma":0.00006907588,"domain_scores_codex":[0.9977097,0.00006212039,0.0006931094,0.0007339052,0.0004731481,0.0003280274],"domain_scores_gemma":[0.9984863,0.0004789585,0.0001637969,0.0004780095,0.000230308,0.0001625646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000162864,0.0001605367,0.0006667174,0.000289874,0.0001427271,0.000005328475,0.0001311392,0.001425984,0.8539976,0.0001496644,0.00008503572,0.1427825],"study_design_scores_gemma":[0.0003443751,0.00002581398,0.002900106,0.0003924466,0.0004185352,0.00002025361,0.0001635828,0.03972207,0.9537007,0.0001623549,0.001687387,0.0004624263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907693,0.001726365,0.003209402,0.0009497894,0.0002222663,0.0003910225,0.000283216,0.0003159018,0.002132717],"genre_scores_gemma":[0.997264,0.000114741,0.001591653,0.00002611359,0.0003570144,0.0003230405,0.0001289805,0.00003677142,0.000157732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1423201,"threshold_uncertainty_score":0.9999829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02300812625691252,"score_gpt":0.2807345476052502,"score_spread":0.2577264213483377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}