{"id":"W4402589716","doi":"10.1055/a-2417-9450","title":"Efficient and Direct Route to 5-Iodo-4H-Quinoxalines via Copper-Catalyzed Double C–N Arylations of 1,2,3-Triiodoarenes: Potential Application towards 5-Substituted 4H-Quinoxalines","year":2024,"lang":"en","type":"article","venue":"Synthesis","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"Deanship of Research, Jordan University of Science and Technology","keywords":"Chemistry; Copper; Catalysis; Combinatorial chemistry; Organic chemistry; Medicinal chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002647162,0.000688077,0.0003155226,0.0002374994,0.0002059483,0.0002118549,0.0005357414,0.0003141195,0.001097905],"category_scores_gemma":[0.0001621395,0.0001998065,0.0002769368,0.0001831207,0.0002533297,0.0003378258,0.0004953336,0.0004755734,0.0004984264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002925207,"about_ca_system_score_gemma":0.0003308907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006370276,"about_ca_topic_score_gemma":0.001374537,"domain_scores_codex":[0.99981,0.00002597233,0.00001884868,0.00004027227,0.00003829756,0.00006665253],"domain_scores_gemma":[0.9999298,0.000007945655,0.00002483236,0.00000958599,0.00001200604,0.00001584634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003917367,0.00003144587,0.0000798969,0.0001696356,0.00001260262,0.0002663449,0.00005997754,0.0002342465,0.9938659,0.0004871133,0.0001250399,0.004628548],"study_design_scores_gemma":[0.00001701775,0.0003203257,0.0004301202,0.000008014135,0.00001936921,0.0003979378,0.00002590476,0.000566817,0.9925368,0.00006398045,0.005598908,0.00001482716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9070305,0.008327737,0.0661317,0.0002874515,0.0002161363,0.0003526253,0.0004693297,0.0004334179,0.01675108],"genre_scores_gemma":[0.984091,0.002266334,0.01067448,0.00003611436,0.0000249861,0.00006105268,0.0001439403,0.00002475515,0.002677294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001097905,"threshold_uncertainty_score":0.003672898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02300812625691252,"score_gpt":0.2807345476052502,"score_spread":0.2577264213483377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}