{"id":"W4402620082","doi":"10.1007/s40259-024-00677-y","title":"Chikungunya Virus Vaccines: A Review of IXCHIQ and PXVX0317 from Pre-Clinical Evaluation to Licensure","year":2024,"lang":"en","type":"review","venue":"BioDrugs","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"Chikungunya; Medicine; Clinical trial; European union; Virology; Alphavirus; Licensure; Virus; Internal medicine; Business","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001584908,0.0007003407,0.001208838,0.001850618,0.0002405965,0.001072795,0.0008159959,0.00106768,0.003563494],"category_scores_gemma":[0.002183641,0.0003533982,0.00123939,0.001385026,0.0003447386,0.001213875,0.0004972822,0.001486053,0.001195617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005513481,"about_ca_system_score_gemma":0.001471321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001084905,"about_ca_topic_score_gemma":0.001796946,"domain_scores_codex":[0.9995011,0.0001269515,0.0001236067,0.00005816542,0.0001489011,0.00004131928],"domain_scores_gemma":[0.9989594,0.0005622206,0.0001776559,0.0000214646,0.0002323727,0.00004685806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003204685,0.0001385099,0.000270709,0.05528148,0.000266625,0.0003120686,0.0001838461,0.0004185187,0.003027643,0.002480383,0.02852948,0.9087703],"study_design_scores_gemma":[0.00007958649,0.0005965937,0.001128133,0.01781745,0.0005587599,0.0009656093,0.00007013931,0.0001014133,0.001045373,0.0008764368,0.9767328,0.0000276762],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003341783,0.9979298,0.0001354651,0.0003774991,0.0001654101,0.0000249271,0.00005313669,0.000007426865,0.0009720768],"genre_scores_gemma":[0.001373463,0.9971237,0.0002985034,0.000482122,0.0001352455,0.00004211458,0.00008212586,0.000003239136,0.0004595402],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003563494,"threshold_uncertainty_score":0.01192105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0731524147698617,"score_gpt":0.4688754399647942,"score_spread":0.3957230251949325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}