{"id":"W4402647045","doi":"10.30895/1991-2919-2024-14-4-386-399","title":"Current and Future Pharmacopoeial Requirements for the Quality of Extemporaneous Medicinal Products: A Review of Regulatory Standards","year":2024,"lang":"en","type":"review","venue":"Regulâtornye issledovaniâ i èkspertiza lekarstvennyh sredstv.","topic":"Safe Handling of Antineoplastic Drugs","field":"Health Professions","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Quality (philosophy); Business; Risk analysis (engineering)","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01924581,0.001167344,0.001342483,0.007129224,0.001047762,0.003052089,0.003133002,0.003226443,0.002381595],"category_scores_gemma":[0.01579472,0.0005144736,0.001358897,0.005679713,0.003514994,0.003865617,0.001551724,0.003821288,0.00146856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003595922,"about_ca_system_score_gemma":0.01572626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007827934,"about_ca_topic_score_gemma":0.004504399,"domain_scores_codex":[0.9854628,0.002378387,0.002557752,0.001080283,0.008064734,0.0004560522],"domain_scores_gemma":[0.9758873,0.007476209,0.003536466,0.0009264895,0.01166239,0.0005111791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001292695,0.0002576895,0.002000604,0.01665315,0.00007537623,0.000534896,0.0007837394,0.001255905,0.006045213,0.04055989,0.05876435,0.8729399],"study_design_scores_gemma":[0.00001774292,0.0001791534,0.004854434,0.01169574,0.0001378895,0.0009094185,0.0004591365,0.000495083,0.0024457,0.005786278,0.9729446,0.0000748054],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00250258,0.9529296,0.009751103,0.01175013,0.002018909,0.0002403958,0.0003979279,0.0001616469,0.02024772],"genre_scores_gemma":[0.02261765,0.9464028,0.01882586,0.004987551,0.001427121,0.0003654788,0.001085198,0.00006188456,0.004226454],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01924581,"threshold_uncertainty_score":0.1017829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1643417752352282,"score_gpt":0.5340631960785597,"score_spread":0.3697214208433315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}