{"id":"W4402659369","doi":"10.1186/s12864-024-10695-3","title":"Unveiling the Brazilian kefir microbiome: discovery of a novel Lactobacillus kefiranofaciens (LkefirU) genome and in silico prospection of bioactive peptides with potential anti-Alzheimer properties","year":2024,"lang":"en","type":"article","venue":"BMC Genomics","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Universidade Federal de Uberlândia; Financiadora de Estudos e Projetos; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Biology; In silico; Microbiome; Prospection; Genome; Computational biology; Genetics; Gene; Geography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003481664,0.0007789825,0.0006030549,0.0005746955,0.00034668,0.0007686386,0.0002097513,0.0005114751,0.0005653851],"category_scores_gemma":[0.0005250148,0.0001857229,0.0009569505,0.0006516249,0.0001595143,0.0003978378,0.0004436682,0.0004573331,0.0001954101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004096905,"about_ca_system_score_gemma":0.0006373412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005297315,"about_ca_topic_score_gemma":0.007380871,"domain_scores_codex":[0.9998562,0.00002364038,0.00001006274,0.00004218028,0.00003418673,0.00003369139],"domain_scores_gemma":[0.9998704,0.00002813078,0.00003787172,0.00001076003,0.00002935909,0.00002339682],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004504453,0.00008816706,0.01483712,0.0004680269,0.00009929446,0.0003051833,0.000262837,0.001890794,0.9624429,0.0001679577,0.0002041862,0.01878317],"study_design_scores_gemma":[0.0001644586,0.002536504,0.3479383,0.000484058,0.001513401,0.003424607,0.00445526,0.04832511,0.5545444,0.001320632,0.03510122,0.0001920233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900659,0.002173163,0.004450031,0.000342147,0.00001590807,0.00003903234,0.001996547,0.00008460054,0.0008326148],"genre_scores_gemma":[0.977187,0.002007321,0.01673312,0.0001156229,0.0000101819,0.00003365621,0.003420773,0.00004407762,0.0004482557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005297315,"threshold_uncertainty_score":0.01053292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0250303456106331,"score_gpt":0.2063053291834102,"score_spread":0.181274983572777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}