{"id":"W4402731997","doi":"10.3390/jcdd11090296","title":"Statins in the Cause and Prevention of Cancer: Confounding by Indication and Mediation by Rhabdomyolysis and Phosphate Toxicity","year":2024,"lang":"en","type":"review","venue":"Journal of Cardiovascular Development and Disease","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Rhabdomyolysis; Medicine; Statin; Cancer; Internal medicine; Cholesterol; Confounding; Toxicity; Pharmacology; Disease; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002246793,0.0008602573,0.003084825,0.002117527,0.0002371932,0.001153549,0.001250943,0.001495379,0.003005523],"category_scores_gemma":[0.003779194,0.0003649467,0.001265669,0.002157397,0.0006638381,0.001088946,0.0006479548,0.002400245,0.001085081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001029283,"about_ca_system_score_gemma":0.001811451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001951421,"about_ca_topic_score_gemma":0.003689221,"domain_scores_codex":[0.9992861,0.0002594973,0.0001243637,0.0001027167,0.0001906426,0.00003670916],"domain_scores_gemma":[0.9974747,0.001845813,0.0001963969,0.00005160774,0.0003546026,0.00007678597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002100458,0.00005467569,0.000527186,0.02977889,0.0007899925,0.0001442707,0.00004255326,0.0002928875,0.0003704239,0.003643597,0.02321048,0.940935],"study_design_scores_gemma":[0.0001447159,0.0002688863,0.005470802,0.02948885,0.002343692,0.001694796,0.0001109285,0.0003193923,0.0006025651,0.008351086,0.9511322,0.00007213342],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003759331,0.9993013,0.0000535931,0.0002883387,0.0001305628,0.000001936784,0.00001154295,0.000002375279,0.0001728514],"genre_scores_gemma":[0.0004923819,0.998841,0.00009715271,0.0002248914,0.0001721406,0.000005198893,0.00002055814,0.000001328263,0.000145323],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003084825,"threshold_uncertainty_score":0.01188236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01447594581192908,"score_gpt":0.3017516446733741,"score_spread":0.287275698861445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}