{"id":"W4402839609","doi":"10.1021/acscatal.4c04400","title":"Direct Deoxygenative Homocoupling of Alcohols to Access C(sp<sup>3</sup>)–C(sp<sup>3</sup>) Bonds via Synergistic Ruthenium/Nickel Catalysis","year":2024,"lang":"en","type":"article","venue":"ACS Catalysis","topic":"Asymmetric Hydrogenation and Catalysis","field":"Chemistry","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Centre in Green Chemistry and Catalysis","funders":"Natural Science Foundation of Qinghai; Fonds Québécois de la Recherche sur la Nature et les Technologies; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; National Natural Science Foundation of China; Canada Research Chairs","keywords":"Ruthenium; Catalysis; Nickel; Chemistry; Medicinal chemistry; Photochemistry; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001129921,0.001227476,0.002020848,0.002623423,0.0005078511,0.0006502979,0.002627335,0.0006478617,0.002099214],"category_scores_gemma":[0.001377207,0.001201516,0.001446866,0.01036106,0.0003391696,0.001091132,0.00118758,0.0008106383,0.001217777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007962701,"about_ca_system_score_gemma":0.000377373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001469402,"about_ca_topic_score_gemma":0.00008256535,"domain_scores_codex":[0.9919937,0.0001231755,0.002098207,0.002355971,0.002062691,0.001366203],"domain_scores_gemma":[0.9937972,0.001267634,0.0005884498,0.002734973,0.0007721231,0.0008396441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006421125,0.003241825,0.005131964,0.004381576,0.03824933,0.001247726,0.03285255,0.4102064,0.2830439,0.001460548,0.01983963,0.1997024],"study_design_scores_gemma":[0.001067441,0.00009051774,0.0001172563,0.0004111694,0.007239862,0.00005585935,0.003420567,0.1758142,0.7955403,0.0002966823,0.01355896,0.002387199],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9583169,0.004362369,0.009999358,0.0006710541,0.0001505863,0.0005860066,0.001265,0.0009572049,0.02369151],"genre_scores_gemma":[0.9860175,0.0002431451,0.000399025,0.0002330638,0.000449397,0.0004933284,0.003713503,0.0002769982,0.008174087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5124964,"threshold_uncertainty_score":0.9995599,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01684863522604466,"score_gpt":0.280640202828687,"score_spread":0.2637915676026423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}