{"id":"W4402868169","doi":"10.1093/molbev/msae201","title":"Widespread Adaptive Introgression of Major Histocompatibility Complex Genes across Vertebrate Hybrid Zones","year":2024,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of New Brunswick; University of British Columbia","funders":"Narodowe Centrum Nauki; Grantová Agentura České Republiky","keywords":"Introgression; Biology; Evolutionary biology; Balancing selection; Major histocompatibility complex; Vertebrate; Allele; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002728073,0.0002269525,0.0003785224,0.0001059924,0.0002196705,0.000009341731,0.0001594937,0.0003401759,0.0001359232],"category_scores_gemma":[0.00003730873,0.0001860444,0.0001136732,0.0001290379,0.001119475,0.0000678565,0.0001814003,0.0002722709,0.0001313651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005983933,"about_ca_system_score_gemma":0.00005099173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002616095,"about_ca_topic_score_gemma":0.00004373849,"domain_scores_codex":[0.998311,0.0004201129,0.0003574617,0.0005017633,0.00002338115,0.0003862354],"domain_scores_gemma":[0.9994182,0.0001081513,0.0001038965,0.0002668668,0.0000799021,0.00002297705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003046833,0.0001009465,0.003819539,0.00005160381,0.0002366284,0.00001326188,0.0001342854,0.000004306321,0.970446,0.01498885,0.0004140758,0.009485831],"study_design_scores_gemma":[0.001434496,0.001079749,0.01159598,0.0001070428,0.0001381331,0.000276019,0.0002028534,0.0007101332,0.9590479,0.01728294,0.007718525,0.0004062225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.920101,0.0481292,0.03004181,0.0002255252,0.0009120051,0.0002602391,0.0001170394,0.0001082443,0.0001049633],"genre_scores_gemma":[0.9989159,0.0001314901,0.0003518237,0.00004751259,0.00002324529,0.00002995353,0.0003008693,0.00001428748,0.0001849876],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07881486,"threshold_uncertainty_score":0.7586672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01328113139693365,"score_gpt":0.2722836472672883,"score_spread":0.2590025158703547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}