{"id":"W4402868169","doi":"10.1093/molbev/msae201","title":"Widespread Adaptive Introgression of Major Histocompatibility Complex Genes across Vertebrate Hybrid Zones","year":2024,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of New Brunswick; University of British Columbia","funders":"Narodowe Centrum Nauki; Grantová Agentura České Republiky","keywords":"Introgression; Biology; Evolutionary biology; Balancing selection; Major histocompatibility complex; Vertebrate; Allele; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008296805,0.0002315771,0.0003759859,0.001123646,0.000373399,0.0004498895,0.0002694355,0.0002300452,0.001163562],"category_scores_gemma":[0.0009582785,0.00009590064,0.000336351,0.0006813805,0.0006766198,0.0002552117,0.0007715601,0.0004387211,0.0002001191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001605391,"about_ca_system_score_gemma":0.0000943123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004233093,"about_ca_topic_score_gemma":0.0009674398,"domain_scores_codex":[0.9994019,0.0001399173,0.0000450665,0.0002549235,0.0001092019,0.00004891409],"domain_scores_gemma":[0.9986475,0.0005380415,0.0003849429,0.000181881,0.00009955378,0.0001480975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004503476,0.00006342675,0.5726328,0.0001503966,0.0004701792,0.0003757577,0.0009775229,0.000598005,0.4063959,0.0002688639,0.00004697061,0.01756973],"study_design_scores_gemma":[0.000005575429,0.0001190683,0.9933807,0.00000353819,0.00004644797,0.000384269,0.0001558705,0.0003068939,0.005258592,0.0001062761,0.0002266034,0.000006103087],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984351,0.0001454661,0.0009865426,0.000005872773,0.000001400526,0.000004975895,0.00008295428,0.00001017174,0.0003274807],"genre_scores_gemma":[0.999239,0.00005257826,0.0004313197,0.00001022532,0.000002155657,0.000005178361,0.0001941999,0.000003382525,0.00006207178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001163562,"threshold_uncertainty_score":0.004387856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01328113139693365,"score_gpt":0.2722836472672883,"score_spread":0.2590025158703547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}